SCHEMBL4997659

SCHEMBL4997659

NC(=O)CC[Si](F)(F)F

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5372245 0.71
SCHEMBL3463747 0.70 TSHR (0.32)
Succinamide SCHEMBL36057 0.69
Succinamide SCHEMBL28157588 0.69 LMNA (0.50)
SCHEMBL10812600 0.69
Succinamide SCHEMBL29631488 0.66
Succinamide SCHEMBL1647263 0.66 LMNA (0.47)
Succinamide SCHEMBL29269227 0.66
Succinamide SCHEMBL21530847 0.66 LMNA (0.47)
Succinamide SCHEMBL28836984 0.66

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7396925-B2 Volatilizable solid phase supports for compound synthesis MIXTURE SCIENCES, INC. (US) 2008-07-08 US disclosed
US-20060241283-A1 Volatilizable solid phase supports for compound synthesis MIXTURE SCIENCES, INC. (US) 2006-10-26 US disclosed
US-7067623-B2 Volatilizable solid phase supports for compound synthesis MIXTURE SCIENCES, INC. (US) 2006-06-27 US disclosed
EP-1147127-B1 VOLATILIZABLE SOLID PHASE SUPPORTS FOR COMPOUND SYNTHESIS MIXTURE SCIENCES INC (US) 2006-06-07 EP disclosed
WO-2005113573-A2 METHOD OF SUPPORT-BASED CHEMICAL SYNTHESIS MIXTURE SCIENCES, INC. (US) 2005-12-01 WO disclosed
US-20050261474-A1 Method of support-based chemical synthesis MIXTURE SCIENCES, INC. 2005-11-24 US disclosed
EP-1147127-A4 VOLATILIZABLE SOLID PHASE SUPPORTS FOR COMPOUND SYNTHESIS MIXTURE SCIENCES INC (US) 2004-03-31 EP disclosed
US-20030135024-A1 Volatilizable solid phase supports for compound synthesis TORREY PINES INSTITUTE FOR MOLECULAR STUDIES 2003-07-17 US disclosed
EP-1147127-A1 VOLATILIZABLE SOLID PHASE SUPPORTS FOR COMPOUND SYNTHESIS Mixture Sciences Inc. (US) 2001-10-24 EP disclosed
WO-2000046238-A1 VOLATILIZABLE SOLID PHASE SUPPORTS FOR COMPOUND SYNTHESIS MIXTURE SCIENCES, INC. (US) 2000-08-10 WO disclosed