SCHEMBL5372245

SCHEMBL5372245

C[Si](C)(C)CCC(N)=O

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4396869 0.86 SOAT1 (0.37)
SCHEMBL5482205 0.81 SOAT1 (0.43)
SCHEMBL3908581 0.74 TSHR (0.31)
SCHEMBL6914208 0.73
SCHEMBL445043 0.73
SCHEMBL2026715 0.71 LMNA (0.44)
SCHEMBL4997659 0.71
SCHEMBL14759998 0.71
SCHEMBL3075248 0.71
SCHEMBL3463747 0.70 TSHR (0.32)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11965111-B2 Surface treatment agent and surface treatment method TOKYO OHKA KOGYO CO., LTD. (JP) 2024-04-23 US disclosed
CN-113474352-A Novel phosphoramidites 罗氏创新中心哥本哈根有限公司 2021-10-01 CN disclosed
US-10941301-B2 Surface treatment method, surface treatment agent, and method for forming film region-selectively on substrate TOKYO OHKA KOGYO CO., LTD. (JP) 2021-03-09 US disclosed
US-20200079962-A1 SURFACE TREATMENT AGENT AND SURFACE TREATMENT METHOD TOKYO OHKA KOGYO CO., LTD. (JP) 2020-03-12 US disclosed
US-20200062968-A1 SURFACE TREATMENT AGENT AND SURFACE TREATMENT METHOD TOKYO OHKA KOGYO CO., LTD. (JP) 2020-02-27 US disclosed
US-20190203054-A1 SURFACE TREATMENT METHOD, SURFACE TREATMENT AGENT, AND METHOD FOR FORMING FILM REGION-SELECTIVELY ON SUBSTRATE TOKYO OHKA KOGYO CO., LTD. (JP) 2019-07-04 US disclosed
US-20070129331-A1 PHARMACEUTICAL COMPOSITIONS AND METHODS OF USE OF LIPOPHILIC, SILICON-SUBSTITUTED, CYCLOOXYGENASE-2 SELECTIVE NON-STEROIDAL ANTI-INFLAMMATORY DRUGS AND DERIVATIVES RND PHARMACEUTICALS, INC. (US) 2007-06-07 US disclosed
CN-1747995-A Resin compositions CIBA SC HOLDING AG (CH) 2006-03-15 CN disclosed