Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.58 |
| ▸ | USP2 | O75604 | 1/20 | 0.58 |
| ▸ | TSHR | P16473 | 1/20 | 0.58 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.58 |
| ▸ | HPGD | P15428 | 1/20 | 0.47 |
| ▸ | ERCC1 | P07992 | 2/20 | 0.46 |
| ▸ | FEN1 | P39748 | 2/20 | 0.46 |
| ▸ | ERCC4 | Q92889 | 2/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | PPID | Q08752 | 1/20 | 0.43 |
| ▸ | PIN1 | Q13526 | 1/20 | 0.42 |
| ▸ | ELANE | P08246 | 1/20 | 0.42 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.41 |
| ▸ | RNASEH1 | O60930 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4737701 | 0.85 | ERCC1 (0.48) | HSD17B10USP2TSHRMAPK1ERCC1 | |
| SCHEMBL3517904 | 0.75 | HPGD (0.45) | HSD17B10USP2TSHRMAPK1HPGD | |
| SCHEMBL4992207 | 0.74 | EGLN3 (0.54) | HSD17B10TSHRHPGDSMN1; SMN2ALDH1A1 | |
| SCHEMBL4649688 | 0.74 | KDM4E (0.44) | HSD17B10USP2HPGDSMN1; SMN2ALDH1A1 | |
| SCHEMBL4737065 | 0.73 | HPGD (0.46) | HPGDERCC1FEN1ERCC4SMN1; SMN2 | |
| SCHEMBL7216561 | 0.72 | ADORA3 (0.60) | HSD17B10USP2TSHRMAPK1HPGD | |
| SCHEMBL3516621 | 0.72 | ALDH1A1 (0.41) | HSD17B10USP2TSHRMAPK1HPGD | |
| SCHEMBL10338070 | 0.71 | ERCC1 (0.55) | HSD17B10USP2TSHRMAPK1HPGD | |
| SCHEMBL24005288 | 0.71 | ALDH1A1 (0.55) | HSD17B10USP2HPGDSMN1; SMN2ALDH1A1 | |
| SCHEMBL4995930 | 0.70 | EGLN3 (0.65) | HSD17B10HPGDALDH1A1LMNAPIN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080171756-A1 | N-Substituted Glycine Derivatives: Prolyl Hydroxylase Inhibitors | SMITHKLINE BEECHAM CORPORATION | 2008-07-17 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080171756-A1 | N-Substituted Glycine Derivatives: Prolyl Hydroxylase Inhibitors | HIF1AN, EGLN2, EGLN3 | HSD17B10 429/4885USP2 2427/4885TSHR 3458/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.