SCHEMBL499856

SCHEMBL499856

COc1cccc(C(=O)c2ccccc2)c1S(=O)(=O)OO

nearest known ligand 0.49

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
STS P08842 1/20 0.49
MAPT P10636 6/20 0.49
KDM4E B2RXH2 2/20 0.49
HSD17B10 Q99714 2/20 0.49
ALOX15 P16050 1/20 0.49
MAPK1 P28482 1/20 0.49
LMNA P02545 4/20 0.48
KMT2A Q03164 3/20 0.48
ALDH1A1 P00352 2/20 0.48
CYP3A4 P08684 1/20 0.48
HPGD P15428 1/20 0.48
RECQL P46063 1/20 0.48
RAB9A P51151 3/20 0.47
NPC1 O15118 3/20 0.46
SMN1; SMN2 Q16637 2/20 0.46
MEN1 O00255 1/20 0.46
HTT P42858 1/20 0.46
NPSR1 Q6W5P4 1/20 0.46
TP53 P04637 1/20 0.45
GAA P10253 1/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2859044 0.99 STS (0.48) STSMAPTKDM4EHSD17B10ALOX15
SCHEMBL1734479 0.85 MAPT (0.57) STSMAPTKDM4EHSD17B10ALOX15
SCHEMBL1161146 0.79 MAPT (0.47) MAPTKDM4EHSD17B10ALOX15MAPK1
SCHEMBL50229 0.78 MAPT (0.64) STSMAPTKDM4EHSD17B10ALOX15
SCHEMBL29573531 0.78 MAPT (0.64) STSMAPTKDM4EHSD17B10ALOX15
Benzophenone SCHEMBL11416830 0.76 MAPT (0.67) STSMAPTKDM4EHSD17B10ALOX15
Bicarbonate SCHEMBL27740092 0.76 MAPT (0.62) STSMAPTKDM4EHSD17B10ALOX15
SCHEMBL11068512 0.75 MAPT (0.57) STSMAPTKDM4EHSD17B10ALOX15
SCHEMBL322169 0.75 MAPT (0.57) STSMAPTKDM4EHSD17B10ALOX15
SCHEMBL29986971 0.75 MAPT (0.57) STSMAPTKDM4EHSD17B10ALOX15

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2543356-A1 SUNBLOCK COMPOSITION Shiseido Company, Ltd. (JP) 2013-01-09 EP claimed
US-20120321576-A1 SUNSCREEN COMPOSITION SHISEIDO COMPANY, LTD. (JP) 2012-12-20 US claimed
EP-2172185-B1 Cosmetic material comprising octyl hydroxy stearate oligomer PARAHERMOSA CO LTD (JP) 2011-11-23 EP claimed
US-10786437-B2 Composition for cosmetics and cosmetics comprising same AJINOMOTO CO., INC (JP) 2020-09-29 US disclosed
US-20200113799-A1 POWDER MODIFYING AGENT, COMPOSITE POWDER AND MAKEUP COSMETIC AJINOMOTO CO., INC. (JP) 2020-04-16 US disclosed
EP-3636247-A1 POWDER MODIFYING AGENT, COMPOSITE POWDER AND MAKEUP COSMETIC Ajinomoto Co., Inc. (JP) 2020-04-15 EP disclosed
EP-2543356-B1 SUNBLOCK COMPOSITION SHISEIDO CO LTD (JP) 2017-01-04 EP disclosed
EP-2543356-A1 SUNBLOCK COMPOSITION Shiseido Company, Ltd. (JP) 2013-01-09 EP disclosed
US-20120321576-A1 SUNSCREEN COMPOSITION SHISEIDO COMPANY, LTD. (JP) 2012-12-20 US disclosed
US-8198335-B2 Cosmetic material PARAHERMOSA CO., LTD. (JP) 2012-06-12 US disclosed
US-8105637-B2 health food and drink contains the pure plant extract, is for patients with abnormality in cerebral blood flow and metabolism of brain disorder; nutraceuticals; free of proanthocyanidins SHIMADA SHINJI (JP) 2012-01-31 US disclosed
EP-2172185-B1 Cosmetic material comprising octyl hydroxy stearate oligomer PARAHERMOSA CO LTD (JP) 2011-11-23 EP disclosed
US-20100087551-A1 COSMETIC MATERIAL PARAHERMOSA CO., LTD. (JP) 2010-04-08 US disclosed
EP-2172185-A2 Cosmetic material comprising octyl hydroxy stearate oligomer Parahermosa Co., Ltd. (JP) 2010-04-07 EP disclosed
US-20080254126-A1 Composition comprising nanoparticle ginkgo biloba extract with the effect of brain function activation SHIMADA SHINJI 2008-10-16 US disclosed