SCHEMBL29986971

SCHEMBL29986971

COc1cccc(C(=O)c2ccccc2)c1OC

nearest known ligand 0.57

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 5/20 0.57
KDM4E B2RXH2 2/20 0.57
HSD17B10 Q99714 2/20 0.57
ALOX15 P16050 1/20 0.57
MAPK1 P28482 1/20 0.57
LMNA P02545 4/20 0.56
L3MBTL1 Q9Y468 1/20 0.56
HPGD P15428 2/20 0.55
CYP3A4 P08684 1/20 0.55
RECQL P46063 1/20 0.55
RAB9A P51151 4/20 0.54
ALDH1A1 P00352 3/20 0.54
NPC1 O15118 4/20 0.54
GAA P10253 2/20 0.53
HTT P42858 2/20 0.53
SMN1; SMN2 Q16637 2/20 0.53
NPSR1 Q6W5P4 1/20 0.53
ELANE P08246 1/20 0.51
TP53 P04637 1/20 0.51
USP2 O75604 1/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL322169 1.00 MAPT (0.57) MAPTKDM4EHSD17B10ALOX15MAPK1
SCHEMBL28095416 0.98 MAPT (0.55) MAPTKDM4EHSD17B10ALOX15MAPK1
Benzoic Acid SCHEMBL28087661 0.95 MAPT (0.53) MAPTKDM4EHSD17B10ALOX15MAPK1
SCHEMBL27507752 0.91 MAPT (0.56) MAPTKDM4EHSD17B10ALOX15MAPK1
SCHEMBL29039855 0.91 LMNA (0.63) MAPTKDM4EHSD17B10ALOX15MAPK1
SCHEMBL2238585 0.89 MAPK1 (0.59) MAPTKDM4EHSD17B10ALOX15MAPK1
SCHEMBL27532250 0.87 MAPT (0.51) MAPTKDM4EHSD17B10ALOX15MAPK1
SCHEMBL3762150 0.87 RAB9A (0.55) MAPTKDM4EHSD17B10MAPK1LMNA
SCHEMBL28872783 0.87 MAPT (0.58) MAPTKDM4EHSD17B10ALOX15MAPK1
Benzoin SCHEMBL28394705 0.86 LMNA (0.54) MAPTKDM4EHSD17B10ALOX15MAPK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-221840200-U Condenser for cooling 4-chloro-3 ',4' -dimethoxy benzophenone mixed solution 甘肃汉隆化工有限公司 2024-10-15 CN disclosed
CN-221558708-U Preparation centrifuge is used in production of 4-chloro-3 ',4' -dimethoxy benzophenone 甘肃汉隆化工有限公司 2024-08-20 CN disclosed
CN-221558708-U Preparation centrifuge is used in production of 4-chloro-3 ',4' -dimethoxy benzophenone 甘肃汉隆化工有限公司 2024-08-20 CN disclosed
CN-117946666-A Phosphorescent and fluorescent double-luminous organic long afterglow crystal material and preparation method thereof 承德石油高等专科学校 2024-04-30 CN disclosed
EP-3562817-B1 ORGANIC MATERIALS WITH SPECIAL OPTICAL EFFECTS CENTRE NAT RECH SCIENT (FR) 2023-11-15 EP disclosed
US-11613513-B2 Organic materials with special optical effects CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (CNRS) (FR) 2023-03-28 US disclosed
US-11407743-B2 Amphiphilic and mesogenic organic dyes for tailor-made reflective low-dimensional materials SORBONNE UNIVERSITE (FR) 2022-08-09 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11613513-B2 Organic materials with special optical effects IK, TYR, MITF MAPT 210/4885KDM4E 3628/4885HSD17B10 3646/4885
US-11407743-B2 Amphiphilic and mesogenic organic dyes for tailor-made reflective low-dimensional materials MITF, LRAT, APOL1 MAPT 406/4885KDM4E 4058/4885HSD17B10 2293/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.