SCHEMBL322169

SCHEMBL322169

COc1cccc(C(=O)c2ccccc2)c1OC

nearest known ligand 0.57

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 5/20 0.57
KDM4E B2RXH2 2/20 0.57
HSD17B10 Q99714 2/20 0.57
ALOX15 P16050 1/20 0.57
MAPK1 P28482 1/20 0.57
LMNA P02545 4/20 0.56
L3MBTL1 Q9Y468 1/20 0.56
HPGD P15428 2/20 0.55
CYP3A4 P08684 1/20 0.55
RECQL P46063 1/20 0.55
RAB9A P51151 4/20 0.54
ALDH1A1 P00352 3/20 0.54
NPC1 O15118 4/20 0.54
GAA P10253 2/20 0.53
HTT P42858 2/20 0.53
SMN1; SMN2 Q16637 2/20 0.53
NPSR1 Q6W5P4 1/20 0.53
ELANE P08246 1/20 0.51
TP53 P04637 1/20 0.51
USP2 O75604 1/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29986971 1.00 MAPT (0.57) MAPTKDM4EHSD17B10ALOX15MAPK1
SCHEMBL28095416 0.98 MAPT (0.55) MAPTKDM4EHSD17B10ALOX15MAPK1
Benzoic Acid SCHEMBL28087661 0.95 MAPT (0.53) MAPTKDM4EHSD17B10ALOX15MAPK1
SCHEMBL27507752 0.91 MAPT (0.56) MAPTKDM4EHSD17B10ALOX15MAPK1
SCHEMBL29039855 0.91 LMNA (0.63) MAPTKDM4EHSD17B10ALOX15MAPK1
SCHEMBL2238585 0.89 MAPK1 (0.59) MAPTKDM4EHSD17B10ALOX15MAPK1
SCHEMBL27532250 0.87 MAPT (0.51) MAPTKDM4EHSD17B10ALOX15MAPK1
SCHEMBL3762150 0.87 RAB9A (0.55) MAPTKDM4EHSD17B10MAPK1LMNA
SCHEMBL28872783 0.87 MAPT (0.58) MAPTKDM4EHSD17B10ALOX15MAPK1
Benzoin SCHEMBL28394705 0.86 LMNA (0.54) MAPTKDM4EHSD17B10ALOX15MAPK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Appears in 2730 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119156330-A Capsule for producing a beverage 雀巢产品有限公司 2024-12-17 CN claimed
US-20240173235-A1 PERSONAL CARE COMPOSITIONS COMPRISING SILAHYDROCARBONS MOMENTIVE PERFORMANCE MATERIALS INC. 2024-05-30 US claimed
EP-4322915-A1 PERSONAL CARE COMPOSITIONS COMPRISING SILAHYDROCARBONS Momentive Performance Materials Inc. (US) 2024-02-21 EP claimed
CN-117550970-A Production method of high-purity dimethyl itaconate 寿光金远东变性淀粉有限公司 2024-02-13 CN claimed
CN-114144386-B Radiation curable composition for coating optical fibers with enhanced high speed processability 科思创(荷兰)有限公司 2023-11-17 CN claimed
CN-116803999-A Preparation method of 3-hydroxy-9H-xanthen-9-one 安徽昊帆生物有限公司 2023-09-26 CN claimed
WO-2023028936-A1 RESIN LENS WITH ENHANCED BLUE LIGHT-RESISTANT PERFORMANCE, AND PREPARATION METHOD THEREFOR 江苏康耐特光学有限公司 2023-03-09 WO claimed
US-20230055665-A1 DELIVERY CARRIER INTO CELL ITO, KABUSIKIKAISYA (JP) 2023-02-23 US claimed
CN-114479735-A Cationic UV curing adhesive and preparation method and application thereof 张河远 2022-05-13 CN claimed
EP-3976544-A1 RADIATON CURABLE COMPOSITIONS FOR COATING OPTICAL FIBER WITH ENHANCED HIGH-SPEED PROCESSABILITY Covestro (Netherlands) B.V. (NL) 2022-04-06 EP claimed
CN-1478083-A Non-yellowing ortho-dialkylaryl substituted triazine ultraviolet light absorbers CYTEC 2004-02-25 CN claimed
WO-2001003652-A9 UV RADIATION REFLECTING OR ABSORBING AGENTS, PROTECTING AGAINST HARMFUL UV RADIATION AND REINFORCING THE NATURAL SKIN BARRIER PHARMASOL GMBH (DE) 2002-09-12 WO claimed
EP-1194111-A2 UV RADIATION REFLECTING OR ABSORBING AGENTS, PROTECTING AGAINST HARMFUL UV RADIATION AND REINFORCING THE NATURAL SKIN BARRIER Pharmasol GmbH (DE) 2002-04-10 EP claimed
WO-2001003652-A2 UV RADIATION REFLECTING OR ABSORBING AGENTS, PROTECTING AGAINST HARMFUL UV RADIATION AND REINFORCING THE NATURAL SKIN BARRIER PHARMASOL GMBH (DE) 2001-01-18 WO claimed
CN-1210512-A Method for hydroxylation of phenolic compounds RODIA CHIMIE S A (FR) 1999-03-10 CN claimed
US-5378734-A UV and moisture-curable organopolysiloxane compositions, cured products therof, and method for making SHIN-ETSU CHEMICAL COMPANY, LTD. (JP) 1995-01-03 US claimed
CN-1020727-C Preparation method of 3- (4-chlorphenyl) -3- (3, 4-dimethoxyphenyl) acrylic acid acyl morpholine SHELL INT RESEARCH (NL) 1993-05-19 CN claimed
CN-1067652-A Preparation method of high-purity 1- (3-chlorphenyl) -4-methyl-7, 8-dimethoxy-5H-2, 3-benzodiazepine * EGYT GYOGYSZERVEGYESZETI GYAR (HU) 1993-01-06 CN claimed
EP-0216084-B1 IMPROVED SUNSCREEN AND MOISTURIZER Richardson-Vicks, Inc. (US) 1991-01-23 EP claimed
CN-86104557-A Adopt photosensitive microcapsules to contain the image forming material of tertiary amines as coinitiators 1987-04-22 CN claimed