Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 2/20 | 0.46 |
| ▸ | TSHR | P16473 | 2/20 | 0.46 |
| ▸ | GLA | P06280 | 1/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | EGFR | P00533 | 3/20 | 0.43 |
| ▸ | AR | P10275 | 4/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | CASP1 | P29466 | 2/20 | 0.41 |
| ▸ | ATM | Q13315 | 2/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | SRC | P12931 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | CASP7 | P55210 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | TLR9 | Q9NR96 | 1/20 | 0.41 |
| ▸ | BACE1 | P56817 | 1/20 | 0.41 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24363277 | 0.79 | ALK (0.46) | ARBACE1HTTADRB2NCF1 | |
| SCHEMBL500930 | 0.79 | AR (0.42) | ARBACE1NR4A2SOS2NOS3 | |
| SCHEMBL30224635 | 0.79 | ALK (0.46) | ARBACE1HTTADRB2NCF1 | |
| SCHEMBL4374398 | 0.79 | TLR8 (0.44) | GAAARALDH1A1CASP1ATM | |
| SCHEMBL669631 | 0.79 | NR4A2 (0.56) | GAACASP1ATMHSD17B10KMT2A | |
| SCHEMBL27964250 | 0.77 | BACE1 (0.51) | GAATSHRGLAPOLBEGFR | |
| SCHEMBL3073397 | 0.75 | NR4A2 (0.66) | TSHREGFRKDM4EALDH1A1CASP1 | |
| SCHEMBL30044428 | 0.75 | NR4A2 (0.66) | TSHREGFRKDM4EALDH1A1CASP1 | |
| SCHEMBL6033548 | 0.75 | HTR1A (0.54) | ARKDM4ENPSR1 | |
| SCHEMBL6033041 | 0.75 | AAK1 (0.46) | EGFRARBACE1NOS3NOS2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114409594-B | Glutathione ratio fluorescent probe of targeting golgi, preparation method and application | 济南大学 | 2023-09-26 | — | — | CN | disclosed |
| CN-114409594-A | Targeted Golgi-body glutathione ratiometric fluorescent probe, preparation method and application | 济南大学 | 2022-04-29 | — | — | CN | disclosed |
| CN-110885312-B | Golgi-targeted cysteine fluorescent probe, and preparation method and application thereof | 济南大学 | 2022-04-12 | — | — | CN | disclosed |
| CN-110885312-A | Golgi-targeted cysteine fluorescent probe, and preparation method and application thereof | 济南大学 | 2020-03-17 | — | — | CN | disclosed |
| US-8106206-B2 | Solid luminescent quinoline compounds | KYUSHU UNIVERSITY, NATIONAL UNIVERSITY CORPORATION (JP) | 2012-01-31 | — | — | US | disclosed |
| US-20110263861-A1 | QUINOLINE COMPOUND | KYUSHU UNIVERSITY, NATIONAL UNIVERSITY CORPORATION (JP) | 2011-10-27 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110263861-A1 | QUINOLINE COMPOUND | GTF3C3, GTF3C2, GTF3C1 | GAA 4157/4885TSHR 3968/4885GLA 3438/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.