Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AR | P10275 | 2/20 | 0.42 |
| ▸ | GAK | O14976 | 2/20 | 0.40 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.35 |
| ▸ | NCF1 | P14598 | 1/20 | 0.35 |
| ▸ | BACE1 | P56817 | 1/20 | 0.34 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.33 |
| ▸ | SLC40A1 | Q9NP59 | 2/20 | 0.33 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.33 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.33 |
| ▸ | GRIN2C | Q14957 | 1/20 | 0.33 |
| ▸ | CCNC | P24863 | 1/20 | 0.33 |
| ▸ | CDK8 | P49336 | 1/20 | 0.33 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.33 |
| ▸ | SOS2 | Q07890 | 1/20 | 0.33 |
| ▸ | PARP1 | P09874 | 1/20 | 0.32 |
| ▸ | NOS3 | P29474 | 1/20 | 0.32 |
| ▸ | NOS2 | P35228 | 1/20 | 0.32 |
| ▸ | GRM4 | Q14833 | 1/20 | 0.32 |
| ▸ | RPS6KA5 | O75582 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24363277 | 0.79 | ALK (0.46) | ARGAKADRB2NCF1BACE1 | |
| SCHEMBL500022 | 0.79 | GAA (0.46) | ARADRB2NCF1BACE1NR4A2 | |
| SCHEMBL4374398 | 0.79 | TLR8 (0.44) | ARADRB2NCF1BACE1GRIN3B | |
| SCHEMBL669631 | 0.79 | NR4A2 (0.56) | ADRB2NCF1SLC40A1NR4A2SOS2 | |
| SCHEMBL30224635 | 0.79 | ALK (0.46) | ARGAKADRB2NCF1BACE1 | |
| SCHEMBL13632508 | 0.76 | GAK (0.42) | GAKCCNCCDK8NR4A2SOS2 | |
| SCHEMBL18544879 | 0.75 | GAK (0.44) | GAKCCNCCDK8NR4A2SOS2 | |
| SCHEMBL6033548 | 0.75 | HTR1A (0.54) | ARGAKGRM4 | |
| SCHEMBL10038578 | 0.74 | ALDH1A1 (0.49) | ARBACE1 | |
| Iodide SCHEMBL11565912 | 0.73 | GAK (0.43) | GAKCCNCCDK8NR4A2SOS2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8106206-B2 | Solid luminescent quinoline compounds | KYUSHU UNIVERSITY, NATIONAL UNIVERSITY CORPORATION (JP) | 2012-01-31 | — | — | US | disclosed |
| US-20110263861-A1 | QUINOLINE COMPOUND | KYUSHU UNIVERSITY, NATIONAL UNIVERSITY CORPORATION (JP) | 2011-10-27 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110263861-A1 | QUINOLINE COMPOUND | GTF3C3, GTF3C2, GTF3C1 | AR 2668/4885GAK 2532/4885ADRB2 404/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.