⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11655431 | 0.81 | ALDH1A1 (0.46) | — | |
| SCHEMBL5510941 | 0.80 | HPGD (0.35) | — | |
| SCHEMBL11892610 | 0.80 | HPGD (0.35) | — | |
| SCHEMBL15345277 | 0.80 | TDP1 (0.36) | — | |
| SCHEMBL15991246 | 0.79 | CYP2C19 (0.46) | — | |
| SCHEMBL9457647 | 0.78 | GABRR1 (0.38) | — | |
| SCHEMBL25963167 | 0.77 | ALDH1A1 (0.42) | — | |
| SCHEMBL14679219 | 0.77 | DDAH1 (0.33) | — | |
| SCHEMBL17229448 | 0.77 | ALDH1A1 (0.37) | — | |
| SCHEMBL36990 | 0.76 | CYP2C19 (0.59) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3212641-A1 | THIAZOLES AS MODULATORS OF RORyt | Janssen Pharmaceutica NV (BE) | 2017-09-06 | — | — | EP | disclosed |
| WO-2016069976-A1 | THIAZOLES AS MODULATORS OF RORyt | JANSSEN PHARMACEUTICA NV (BE) | 2016-05-06 | — | — | WO | disclosed |
| US-8481233-B2 | Organic photoreceptor, image forming apparatus and process cartridge | KONICA MINOLTA BUSINESS TECHNOLOGIES, INC. (JP) | 2013-07-09 | — | — | US | disclosed |
| US-20080292980-A1 | ORGANIC PHOTORECEPTOR, IMAGE FORMING APPARATUS AND PROCESS CARTRIDGE | KONICA MINOLTA BUSINESS TECHNOLOGIES, INC. (JP) | 2008-11-27 | — | — | US | disclosed |
| US-4740567-A | IMPROVED METAL ADHESION AND CORROSION RESISTANCE | CARGILL, INCORPORATED (US) | 1988-04-26 | — | — | US | disclosed |
| US-4649173-A | COATING | CARGILL, INCORPORATED (US) | 1987-03-10 | — | — | US | disclosed |