SCHEMBL5000641

SCHEMBL5000641

COC(=O)c1cc(Oc2ccc(I)cc2)cc(C(=O)OC)c1

nearest known ligand 0.53

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
USP2 O75604 1/20 0.53
CA1 P00915 3/20 0.47
CA2 P00918 3/20 0.47
CA12 O43570 2/20 0.44
CA7 P43166 2/20 0.44
CA9 Q16790 2/20 0.44
CA14 Q9ULX7 2/20 0.44
MAPT P10636 4/20 0.43
POLB P06746 3/20 0.43
KDM4E B2RXH2 2/20 0.43
XDH P47989 2/20 0.43
LMNA P02545 2/20 0.43
GAA P10253 2/20 0.43
NFKB1 P19838 1/20 0.43
GFER P55789 1/20 0.43
NFKB2 Q00653 1/20 0.43
RELA Q04206 1/20 0.43
FUT7 Q11130 1/20 0.43
TDP1 Q9NUW8 1/20 0.43
L3MBTL1 Q9Y468 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6350638 0.84 CA1 (0.60) USP2CA1CA2CA12CA7
SCHEMBL6136142 0.83 POLB (0.44) USP2CA1CA2CA12CA7
SCHEMBL5000622 0.83 USP2 (0.60) USP2CA1CA2CA12CA7
SCHEMBL184785 0.83 KDM4E (0.58) USP2CA1CA2CA12CA7
SCHEMBL10895053 0.83 USP2 (0.53) USP2CA1CA2CA12CA7
SCHEMBL16247158 0.82 TSHR (0.59) USP2CA1CA2CA12CA7
SCHEMBL28479980 0.81 USP2 (0.55) USP2CA1CA2MAPTPOLB
SCHEMBL25314649 0.80 PARP15 (0.57) USP2CA1CA2MAPTPOLB
SCHEMBL10078186 0.79 USP2 (0.56) USP2CA1CA2CA12CA7
SCHEMBL472700 0.79 USP2 (0.49) USP2CA1CA2CA12CA7

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8337982-B2 Comprising first repeating unit obtained by reaction of bisaminophenol compound and dicarboxylic acid, at least one of which has diamondoid structure and second repeating unit obtained by reaction of bisaminophenol compound having no diamondoid structure and dicarboxylic acid; heat resistance SUMITOMO BAKELITE CO., LTD. (JP) 2012-12-25 US disclosed
US-20080206548-A1 Benzoxazole Resin Precursor, Polybenzoxazole Resin, Resin Film And Semiconductor Device SUMITOMO BAKELITE CO., LTD (JP) 2008-08-28 US disclosed
EP-1832619-A1 BENZOXAZOLE RESIN PRECURSOR, POLYBENZOXAZOLE RESIN, RESIN FILM, AND SEMICONDUCTOR DEVICE Sumitomo Bakelite Company, Limited (JP) 2007-09-12 EP disclosed
US-6949674-B2 Aromatic carboxylic acids, acid halides thereof and processes for preparing both SUMITOMO BAKELITE COMPANY, LTD. (JP) 2005-09-27 US disclosed
US-20040068139-A1 Aromatic carboxylic acids, acid halides thereof and processes for preparing both SUMITOMO BAKELITE COMPANY, LTD. (JP) 2004-04-08 US disclosed
EP-1346975-A1 AROMATIC CARBOXYLIC ACIDS, ACID HALIDES THEREOF AND PROCESSES FOR PREPARING BOTH SUMITOMO BAKELITE CO., LTD. (JP) 2003-09-24 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20040068139-A1 Aromatic carboxylic acids, acid halides thereof and processes for preparing both CCR1, CCRL2, CCR6 USP2 579/4885CA1 592/4885CA2 986/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.