Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAD52 | P43351 | 1/20 | 0.47 |
| ▸ | MAP4K1 | Q92918 | 1/20 | 0.45 |
| ▸ | PIM2 | Q9P1W9 | 10/20 | 0.45 |
| ▸ | PIM1 | P11309 | 1/20 | 0.42 |
| ▸ | CSNK2A2 | P19784 | 1/20 | 0.42 |
| ▸ | CSNK2A1 | P68400 | 1/20 | 0.42 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.38 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.38 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.38 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.38 |
| ▸ | FYN | P06241 | 1/20 | 0.38 |
| ▸ | CNR1 | P21554 | 1/20 | 0.38 |
| ▸ | DHFR | P00374 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4996922 | 0.84 | PIM2 (0.47) | RAD52PIM2PIM1CSNK2A2CSNK2A1 | |
| SCHEMBL4987364 | 0.82 | HRH2 (0.48) | RAD52PIM2PIM1CSNK2A2CSNK2A1 | |
| SCHEMBL4997537 | 0.82 | CYP11B1 (0.46) | RAD52PIM2PIM1CSNK2A2CSNK2A1 | |
| SCHEMBL4997813 | 0.82 | PIK3CA (0.55) | RAD52PIM2PIM1CSNK2A2CSNK2A1 | |
| SCHEMBL4996238 | 0.81 | NPC1 (0.50) | RAD52PIM2PIM1CSNK2A2CSNK2A1 | |
| SCHEMBL4997181 | 0.81 | MAPT (0.47) | RAD52PIM2PIM1CSNK2A2CSNK2A1 | |
| SCHEMBL4997769 | 0.81 | PIM2 (0.52) | RAD52MAP4K1PIM2PIM1CSNK2A2 | |
| SCHEMBL4995459 | 0.79 | CYP11B1 (0.48) | RAD52PIM2CYP11B1CYP11B2DHFR | |
| SCHEMBL4997692 | 0.79 | PIM2 (0.52) | RAD52PIM2PIM1CSNK2A2CSNK2A1 | |
| SCHEMBL4997532 | 0.79 | CNR2 (0.49) | RAD52PIM2PIM1CYP11B1CYP11B2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080194574-A1 | Pyrazine Derivatives As Effective Compounds Against Infectious Diseases | AXXIMA PHARMACEUTICALS AG (DE) | 2008-08-14 | — | — | US | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080194574-A1 | Pyrazine Derivatives As Effective Compounds Against Infectious Diseases | PRNP, PSEN1, PPP5C | RAD52 1663/4885MAP4K1 980/4885PIM2 1679/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.