SCHEMBL5000810

SCHEMBL5000810

COC(=O)c1cc(Oc2ccc([N+](=O)[O-])cc2)cc(C(=O)OC)c1

nearest known ligand 0.66

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 4/20 0.66
KMT2A Q03164 4/20 0.66
KDM4E B2RXH2 1/20 0.57
POLB P06746 4/20 0.56
MAPT P10636 3/20 0.55
NPSR1 Q6W5P4 2/20 0.55
NPC1 O15118 2/20 0.55
RAB9A P51151 2/20 0.55
MAPK1 P28482 1/20 0.55
MYOC Q99972 1/20 0.55
SRD5A2 P31213 1/20 0.54
FFAR1 O14842 1/20 0.52
HSPB1 P04792 1/20 0.50
CRHBP P24387 1/20 0.50
CRHR2 Q13324 1/20 0.50
ALDH1A1 P00352 2/20 0.48
HPGD P15428 1/20 0.48
SMN1; SMN2 Q16637 2/20 0.48
USP2 O75604 1/20 0.48
HTT P42858 1/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5695804 0.97 MEN1 (0.70) MEN1KMT2AKDM4EPOLBMAPT
SCHEMBL1030253 0.92 MEN1 (0.59) MEN1KMT2AKDM4EPOLBMAPT
SCHEMBL31504041 0.89 POLB (0.69) MEN1KMT2AKDM4EPOLBMAPT
SCHEMBL2656207 0.88 MEN1 (0.59) MEN1KMT2AKDM4EPOLBMAPT
SCHEMBL31504019 0.87 KDM4E (0.72) MEN1KMT2AKDM4EPOLBMAPT
SCHEMBL18297190 0.86 KMT2A (0.61) MEN1KMT2APOLBMAPTALDH1A1
SCHEMBL28992367 0.85 POLB (0.56) MEN1KMT2AKDM4EPOLBMAPT
SCHEMBL15055075 0.85 HSPB1 (0.55) MEN1KMT2AKDM4EPOLBMAPT
SCHEMBL2885990 0.85 MAPT (0.56) MEN1KMT2AKDM4EPOLBMAPT
SCHEMBL3514553 0.84 KMT2A (0.53) MEN1KMT2AKDM4EPOLBMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8337982-B2 Comprising first repeating unit obtained by reaction of bisaminophenol compound and dicarboxylic acid, at least one of which has diamondoid structure and second repeating unit obtained by reaction of bisaminophenol compound having no diamondoid structure and dicarboxylic acid; heat resistance SUMITOMO BAKELITE CO., LTD. (JP) 2012-12-25 US disclosed
US-20080206548-A1 Benzoxazole Resin Precursor, Polybenzoxazole Resin, Resin Film And Semiconductor Device SUMITOMO BAKELITE CO., LTD (JP) 2008-08-28 US disclosed
EP-1832619-A1 BENZOXAZOLE RESIN PRECURSOR, POLYBENZOXAZOLE RESIN, RESIN FILM, AND SEMICONDUCTOR DEVICE Sumitomo Bakelite Company, Limited (JP) 2007-09-12 EP disclosed
US-6949674-B2 Aromatic carboxylic acids, acid halides thereof and processes for preparing both SUMITOMO BAKELITE COMPANY, LTD. (JP) 2005-09-27 US disclosed
CN-1200925-C Aromatic carboxylic acid compound, acid halide derivative thereof, and process for producing the same SUMITOMO BAKELITE CO (JP) 2005-05-11 CN disclosed
US-20040195552-A1 useful as powders or pellets for incorporation into a variety of thermoplastic resins; diacidic anthraquinone compounds WEAVER MAX ALLEN (US) 2004-10-07 US disclosed
US-6776930-B2 POLYMER BONDED TO DYE EASTMAN KODAK COMPANY 2004-08-17 US disclosed
US-20040068139-A1 Aromatic carboxylic acids, acid halides thereof and processes for preparing both SUMITOMO BAKELITE COMPANY, LTD. (JP) 2004-04-08 US disclosed
CN-1474800-A Aromatic carboxylic acid compound, acid halide derivative thereof, and process for producing the same 住友电木株式会社 2004-02-11 CN disclosed
EP-1346975-A1 AROMATIC CARBOXYLIC ACIDS, ACID HALIDES THEREOF AND PROCESSES FOR PREPARING BOTH SUMITOMO BAKELITE CO., LTD. (JP) 2003-09-24 EP disclosed
US-20010023938-A1 Polymer bonded to dye ALLEN MAX (US) 2001-09-27 US disclosed
US-6197223-B1 REACTING DIACIDIC MONOMER HAVING FORMULA H--A--H, COMPRISING 1 TO 100 MOLE % OF LIGHT-ABSORBING MONOMER HAVING A LIGHT ABSORPTION MAXIMUM BETWEEN 300 NM AND 1200 NM AND 99-0 MOLE % OF A NON-LIGHT ABSORBING MONOMER WITH ORGANIC COMPOUND EASTMAN CHEMICAL COMPANY 2001-03-06 US disclosed
CN-1245516-A Method for preparing light-absorbing polymer composition EASTMAN CHEM CO (US) 2000-02-23 CN disclosed
EP-0948570-A1 METHOD FOR PREPARING LIGHT-ABSORBING POLYMERIC COMPOSITIONS EASTMAN CHEMICAL COMPANY (US) 1999-10-13 EP disclosed
WO-1998023690-A9 METHOD FOR PREPARING LIGHT-ABSORBING POLYMERIC COMPOSITIONS 1998-09-17 WO disclosed
WO-1998023690-A1 METHOD FOR PREPARING LIGHT-ABSORBING POLYMERIC COMPOSITIONS EASTMAN CHEMICAL COMPANY (US) 1998-06-04 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20040068139-A1 Aromatic carboxylic acids, acid halides thereof and processes for preparing both CCR1, CCRL2, CCR6 MEN1 4822/4885KMT2A 3062/4885KDM4E 3633/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.