Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | TAAR1 | Q96RJ0 | 2/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16441855 | 0.70 | ALDH1A1 (0.36) | ALDH1A1TAAR1TSHRSMN1; SMN2 | |
| SCHEMBL25396410 | 0.70 | — | — | |
| SCHEMBL17372035 | 0.65 | KMT2A (0.42) | ALDH1A1SMN1; SMN2 | |
| SCHEMBL2028133 | 0.65 | — | — | |
| SCHEMBL18481885 | 0.64 | KMT2A (0.38) | SMN1; SMN2 | |
| SCHEMBL1268699 | 0.64 | SMN1; SMN2 (0.35) | SMN1; SMN2 | |
| SCHEMBL12475080 | 0.63 | SMN1; SMN2 (0.47) | ALDH1A1SMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL2032274 | 0.63 | — | — | |
| SCHEMBL5628771 | 0.62 | SMN1; SMN2 (0.50) | ALDH1A1TAAR1SMN1; SMN2 | |
| SCHEMBL14215771 | 0.60 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7416868-B2 | Polyene polyketides, processes for their production and their use as a pharmaceutical | THALLION PHARMACEUTICALS, INC. (CA) | 2008-08-26 | — | — | US | disclosed |
| US-7375088-B2 | Polyene polyketides, processes for their production and their use as a pharmaceutical | THALLION PHARMACEUTICALS INC. (CA) | 2008-05-20 | — | — | US | disclosed |
| US-20070275436-A1 | Polyene polyketides, processes for their production and their use as a pharmaceutical | ECOPIA BIOSCIENCES, INC. | 2007-11-29 | — | — | US | disclosed |
| EP-1585752-B1 | POLYENE POLYKETIDES, PROCESSES FOR THEIR PRODUCTION AND THEIR USE AS A PHARMACEUTICAL | THALLION PHARMACEUTICALS INC (CA) | 2007-11-21 | — | — | EP | disclosed |
| EP-1585752-A1 | POLYENE POLYKETIDES, PROCESSES FOR THEIR PRODUCTION AND THEIR USE AS A PHARMACEUTICAL | Ecopia Biosciences Inc. (CA) | 2005-10-19 | — | — | EP | disclosed |
| US-20050187167-A1 | Polyene polyketides, processes for their production and their use as a pharmaceutical | ECOPIA BIOSCIENCES, INC. | 2005-08-25 | — | — | US | disclosed |
| WO-2004065401-A1 | POLYENE POLYKETIDES, PROCESSES FOR THEIR PRODUCTION AND THEIR USE AS A PHARMACEUTICAL | ECOPIA BIOSCIENCES INC. (CA) | 2004-08-05 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070275436-A1 | Polyene polyketides, processes for their production and their use as a pharmaceutical | IPMK, PANK3, PANK1 | ALDH1A1 4091/4885TAAR1 3701/4885TSHR 4148/4885 |
| US-20050187167-A1 | Polyene polyketides, processes for their production and their use as a pharmaceutical | IPMK, PANK3, PANK1 | ALDH1A1 4091/4885TAAR1 3701/4885TSHR 4148/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.