SCHEMBL1268699

SCHEMBL1268699

O=C(O)C1=C(C(=O)O)C(=O)CCC1=O

nearest known ligand 0.37

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
SMN1; SMN2 Q16637 1/20 0.35
CA12 O43570 1/20 0.30
CA1 P00915 1/20 0.30
CA9 Q16790 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12475080 0.73 SMN1; SMN2 (0.47) SMN1; SMN2
SCHEMBL9635649 0.69 CA1 (0.40) CA12CA1CA9
SCHEMBL197756 0.67
SCHEMBL1290379 0.67 FGFR1 (0.37) SMN1; SMN2CA1CA9
SCHEMBL11757970 0.63 TSHR (0.34)
SCHEMBL11757980 0.63 TSHR (0.34)
Bicarbonate SCHEMBL10505866 0.62 TRIM24 (0.41) SMN1; SMN2CA1CA9
SCHEMBL11135748 0.60 TYMS (0.34)
SCHEMBL168735 0.60 PYGM (0.35) CA1CA9
SCHEMBL1286030 0.60 PYGM (0.35) CA1CA9

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 22 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11028121-B2 Multisignal labeling reagents and processes and uses therefor ENZO LIFE SCIENCES, INC. (US) 2021-06-08 US disclosed
US-20200270297-A1 MULTISIGNAL LABELING REAGENTS AND PROCESSES AND USES THEREFOR ENZO LIFE SCIENCE, INC. (US) 2020-08-27 US disclosed
US-10647740-B2 Multisignal labeling reagents and processes and uses therefor ENZO LIFE SCIENCE, INC. (US) 2020-05-12 US disclosed
US-10640529-B2 Multisignal labeling reagents and processes and uses therefor ENZO LIFE SCIENCES, INC. (US) 2020-05-05 US disclosed
EP-1489422-B1 Multisignal labeling reagents, processes and uses therefor ENZO LIFE SCIENCES INC (US) 2018-06-06 EP disclosed
US-20180127455-A1 MULTISIGNAL LABELING REAGENTS AND PROCESSES AND USES THEREFOR Enzo Life Science, Inc., c/o Enzo Biochem, Inc. (US) 2018-05-10 US disclosed
US-20180127456-A1 MULTISIGNAL LABELING REAGENTS AND PROCESSES AND USES THEREFOR Enzo Life Science, Inc., c/o Enzo Biochem, Inc. (US) 2018-05-10 US disclosed
US-9884889-B2 Multisignal labeling reagents and processes and uses therefor ENZO LIFE SCIENCES, INC. (US) 2018-02-06 US disclosed
US-20160025716-A1 MULTISIGNAL LABELING REAGENTS AND PROCESSES AND USES THEREFOR Enzo Life Science, Inc., c/o Enzo Biochem, Inc. (US) 2016-01-28 US disclosed
US-9156986-B2 Multisignal labeling reagents and processes and uses therefor ENZO LIFE SCIENCES, INC. (US) 2015-10-13 US disclosed
US-8389701-B2 Multisignaling oligomeric or polymeric compositions comprising labeled moieties and binding partners ENZO LIFE SCIENCES, INC. (US) 2013-03-05 US disclosed
US-8389702-B2 Multi-oligomeric or multi-polymeric compositions comprising labeled moieties and binding partners ENZO LIFE SCIENCES, INC. (US) 2013-03-05 US disclosed
WO-2012128898-A1 MULTISIGNAL LABELING REAGENTS AND PROCESSES AND USES THEREFOR ENZO LIFE SCIENCES, INC. (US) 2012-09-27 WO disclosed
US-20110318788-A1 Multisignal labeling reagents and processes and uses therefor ENZO LIFE SCIENCES, INC., C/O ENZO BIOCHEM, INC. (US) 2011-12-29 US disclosed
US-20110028692-A1 Multisignaling oligomeric or polymeric compositions comprising labeled moieties and binding partners ENZO LIFE SCIENCES, INC. C/O ENZO BIOCHEM, INC. (US) 2011-02-03 US disclosed
US-20100324268-A1 Multi-oligomeric or multi--polymeric compositions comprising labeled moieties and binding partners ENZO LIFE SCIENCES, INC. C/O ENZO BIOCHEM, INC. (US) 2010-12-23 US disclosed
US-20090258374-A1 Multisignal Labeling Reagents, and Processes and Uses Therefor ENZO LIFE SCIENCES, INC. 2009-10-15 US disclosed
US-7514551-B2 Multisignal labeling reagents, and processes and uses therefor ENZO LIFE SCIENCES, INC. (US) 2009-04-07 US disclosed
EP-1489422-A2 Multisignal labeling reagents, processes and uses therefor Enzo Life Sciences, Inc., c/o Enzo Biochem, Inc. (US) 2004-12-22 EP disclosed
US-20040198971-A1 Multisignal labeling reagents, and processes and uses therefor ENZO LIFE SCIENCES, INC. 2004-10-07 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (10 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10647740-B2 Multisignal labeling reagents and processes and uses therefor PCNA, LIG4, LIG1 SMN1; SMN2 4478/4885CA12 4680/4885CA1 4780/4885
US-20110318788-A1 Multisignal labeling reagents and processes and uses therefor PCNA, LIG4, LIG1 SMN1; SMN2 4478/4885CA12 4680/4885CA1 4780/4885
US-20040198971-A1 Multisignal labeling reagents, and processes and uses therefor HASPIN, HADHB, SPPL2B SMN1; SMN2 4597/4885CA12 1303/4885CA1 2583/4885
US-10640529-B2 Multisignal labeling reagents and processes and uses therefor PCNA, LIG4, LIG1 SMN1; SMN2 4478/4885CA12 4680/4885CA1 4780/4885
US-20110028692-A1 Multisignaling oligomeric or polymeric compositions comprising labeled moieties and binding partners PICALM, CLTB, PHAX SMN1; SMN2 4025/4885CA12 2564/4885CA1 3016/4885
US-20180127455-A1 MULTISIGNAL LABELING REAGENTS AND PROCESSES AND USES THEREFOR PCNA, LIG4, LIG1 SMN1; SMN2 4478/4885CA12 4680/4885CA1 4780/4885
US-20100324268-A1 Multi-oligomeric or multi--polymeric compositions comprising labeled moieties and binding partners PICALM, CLTB, PCBP1 SMN1; SMN2 3665/4885CA12 2603/4885CA1 3176/4885
US-20180127456-A1 MULTISIGNAL LABELING REAGENTS AND PROCESSES AND USES THEREFOR PCNA, LIG4, LIG1 SMN1; SMN2 4478/4885CA12 4680/4885CA1 4780/4885
US-11028121-B2 Multisignal labeling reagents and processes and uses therefor PCNA, LIG4, LIG1 SMN1; SMN2 4478/4885CA12 4680/4885CA1 4780/4885
US-20200270297-A1 MULTISIGNAL LABELING REAGENTS AND PROCESSES AND USES THEREFOR PCNA, LIG4, LIG1 SMN1; SMN2 4478/4885CA12 4680/4885CA1 4780/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.