SCHEMBL5002489

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL4164989	0.85	NR3C2 (0.52)	ARNR3C1PGRNR3C2MAPT
	SCHEMBL4166513	0.85	AR (0.66)	ARNR3C1PGRNR3C2MAPT
	SCHEMBL4175440	0.82	AR (0.59)	ARNR3C1PGRNR3C2MAPT
	SCHEMBL4168200	0.82	AR (0.59)	ARNR3C1PGRNR3C2MAPT
	SCHEMBL4161563	0.82	AR (0.58)	ARNR3C1PGRNR3C2MAPT
	SCHEMBL4173954	0.80	PGR (0.73)	ARNR3C1PGRNR3C2MEN1
	SCHEMBL4164904	0.78	NR3C1 (0.40)	ARNR3C1PGRNR3C2L3MBTL1
	SCHEMBL4164907	0.78	NR3C1 (0.40)	ARNR3C1PGRNR3C2L3MBTL1
	SCHEMBL4160670	0.76	NR3C1 (1.00)	ARNR3C1PGRNR3C2MAPT
	SCHEMBL4157439	0.76	AR (0.69)	ARNR3C1PGRNR3C2MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.