SCHEMBL500509

SCHEMBL500509

CC(=O)OC(=O)c1cccc(C(C)=O)c1C(=O)OC(C)=O

nearest known ligand 0.42

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 2/20 0.42
THRB P10828 1/20 0.38
ITGB1 P05556 1/20 0.37
ITGA5 P08648 1/20 0.37
CA12 O43570 2/20 0.36
CA1 P00915 2/20 0.36
CA2 P00918 2/20 0.36
CA7 P43166 2/20 0.36
CA9 Q16790 2/20 0.36
CA14 Q9ULX7 2/20 0.36
KDM4E B2RXH2 4/20 0.36
ALDH1A1 P00352 4/20 0.36
HSD17B10 Q99714 4/20 0.36
LMNA P02545 4/20 0.36
HPGD P15428 2/20 0.36
SMN1; SMN2 Q16637 2/20 0.36
MAPK1 P28482 1/20 0.36
TSHR P16473 5/20 0.35
TDP1 Q9NUW8 2/20 0.35
ESR1 P03372 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5006514 0.82 TSHR (0.47) KMT2AITGB1ITGA5KDM4EALDH1A1
SCHEMBL2778 0.79 TSHR (0.52) ITGB1ITGA5KDM4EALDH1A1HSD17B10
SCHEMBL30084385 0.79 TSHR (0.52) ITGB1ITGA5KDM4EALDH1A1HSD17B10
SCHEMBL28769090 0.78 CA1 (0.59) KMT2ACA12CA1CA2CA7
Acetone SCHEMBL29281281 0.77 TSHR (0.50) ITGB1ITGA5KDM4EALDH1A1HSD17B10
SCHEMBL6383298 0.77 TSHR (0.50) ITGB1ITGA5KDM4EALDH1A1HSD17B10
SCHEMBL1896602 0.77 TSHR (0.50) ITGB1ITGA5KDM4EALDH1A1HSD17B10
SCHEMBL30401364 0.76 ITGB1 (0.38) KMT2AITGB1ITGA5KDM4EALDH1A1
SCHEMBL9897059 0.76 ITGB1 (0.38) KMT2AITGB1ITGA5CA12CA1
Acetic Acid SCHEMBL28536661 0.75 TSHR (0.48) ITGB1ITGA5CA12CA1CA2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 232 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2006002031-A1 SUSTAINED RELEASE DOSAGE FORMS ANDRX CORPORATION (US) 2006-01-05 WO claimed
US-20050276849-A1 Sustained release dosage forms ANDRX CORPORATION 2005-12-15 US claimed
US-5178866-A DOSAGE FORM FOR DELIVERING DRUG TO THE INTESTINE ALZA CORPORATION (US) 1993-01-12 US claimed
US-4693895-A Colon delivery system ALZA CORPORATION (US) 1987-09-15 US claimed
US-4627851-A Colonic-therapeutic delivery system ALZA CORPORATION (US) 1986-12-09 US claimed
US-11944707-B2 Dual release dosage form capsule and methods, devices and systems for making same Gel Cap Technologies, LLC (US) 2024-04-02 US disclosed
CN-112741816-A Novel colon drug delivery system 江苏集萃新型药物制剂技术研究所有限公司 2021-05-04 CN disclosed
EP-3651721-A1 DUAL RELEASE DOSAGE FORM CAPSULE AND METHODS, DEVICES AND SYSTEMS FOR MAKING SAME Gel Cap Technologies, LLC (US) 2020-05-20 EP disclosed
US-20190307699-A1 DUAL RELEASE DOSAGE FORM CAPSULE AND METHODS, DEVICES AND SYSTEMS FOR MAKING SAME Gel Cap Technologies, LLC (US) 2019-10-10 US disclosed
US-10376471-B2 Dual release dosage form capsule and methods, devices and systems for making same Gel Cap Technologies, LLC (US) 2019-08-13 US disclosed
WO-2019014273-A1 DUAL RELEASE DOSAGE FORM CAPSULE AND METHODS, DEVICES AND SYSTEMS FOR MAKING SAME Gel Cap Technologies, LLC (US) 2019-01-17 WO disclosed
US-20190008781-A1 DUAL RELEASE DOSAGE FORM CAPSULE AND METHODS, DEVICES AND SYSTEMS FOR MAKING SAME Gel Cap Technologies, LLC (US) 2019-01-10 US disclosed
US-4961932-A Plurality of tiny pills in liquid dosage form ALZA CORPORATION (US) 1990-10-09 US disclosed
US-4904474-A Delivery of drug to colon by oral disage form ALZA CORPORATION (US) 1990-02-27 US disclosed
US-4853229-A Method for adminstering tiny pills ALZA CORPORATION (US) 1989-08-01 US disclosed
EP-0313992-A1 Plurality of tiny pills in liquid dosage form ALZA CORPORATION (US) 1989-05-03 EP disclosed
US-4705515-A Dosage form for administering drug of the colon ALZA CORPORATION (US) 1987-11-10 US disclosed
US-4693895-A Colon delivery system ALZA CORPORATION (US) 1987-09-15 US disclosed
US-4627851-A Colonic-therapeutic delivery system ALZA CORPORATION (US) 1986-12-09 US disclosed
US-4608048-A Dispensing device with drug delivery patterns ALZA CORPORATION (US) 1986-08-26 US disclosed