SCHEMBL500563

SCHEMBL500563

CCc1ccc(C(C)c2ccc(CC)cc2)cc1

nearest known ligand 0.56

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TSHR P16473 1/20 0.56
MAPK1 P28482 1/20 0.56
ATM Q13315 1/20 0.56
TDP1 Q9NUW8 1/20 0.56
L3MBTL1 Q9Y468 1/20 0.56
ESR1 P03372 2/20 0.48
ESR2 Q92731 2/20 0.48
PDCD1 Q15116 1/20 0.48
CD274 Q9NZQ7 1/20 0.48
TP53 P04637 1/20 0.46
TAAR1 Q96RJ0 1/20 0.44
CYP2A6 P11509 1/20 0.42
LPL P06858 1/20 0.42
LIPG Q9Y5X9 1/20 0.42
AKR1C3 P42330 1/20 0.41
AKR1C2 P52895 1/20 0.41
ALDH1A1 P00352 2/20 0.41
LMNA P02545 2/20 0.41
HPGD P15428 1/20 0.41
CA2 P00918 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL444227 0.91 TP53 (0.56) TSHRMAPK1ATMTDP1L3MBTL1
SCHEMBL6546683 0.91 ATM (0.48) TSHRMAPK1ATMTDP1L3MBTL1
SCHEMBL24114033 0.89 TSHR (0.47) TSHRMAPK1ATMTDP1L3MBTL1
SCHEMBL11662131 0.89 ESR1 (0.70) TSHRMAPK1ATMTDP1L3MBTL1
SCHEMBL29173275 0.87 L3MBTL1 (0.45) TSHRMAPK1ATMTDP1L3MBTL1
SCHEMBL11849097 0.85 TSHR (0.46) TSHRMAPK1ATMTDP1L3MBTL1
SCHEMBL139408 0.83 L3MBTL1 (0.56) TSHRMAPK1ATMTDP1L3MBTL1
SCHEMBL29174341 0.83 TYR (0.55) TSHRMAPK1ATMTDP1L3MBTL1
Ethylbenzene SCHEMBL28047180 0.82 TP53 (0.67) TP53TAAR1CYP2A6LMNA
SCHEMBL11089722 0.82 LOXL2 (0.50) TSHRMAPK1TDP1L3MBTL1ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 74 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4390194-A DYE-PRECURSOR IN SOLVENT MIXTURE OF 1-METHYL-3-PHENYLINDANE AND A DIARYLALKANE NIPPON PETROCHEMICALS COMPANY, LIMITED (JP) 1983-06-28 US claimed
WO-2025132758-A1 PESTICIDALLY ACTIVE QUINAZOLINE COMPOUNDS SYNGENTA CROP PROTECTION AG (CH) 2025-06-26 WO disclosed
CN-110506040-A Kill the oxadiazole derivatives of microorganism SYNGENTA PARTICIPATIONS AG 2019-11-26 CN disclosed
CN-110392683-A Kill the oxadiazole derivatives of microorganism 先正达参股股份有限公司 2019-10-29 CN disclosed
CN-110382492-A Microbicidal oxadiazole derivatives 先正达参股股份有限公司 2019-10-25 CN disclosed
CN-106661021-B Harmful organism active heterocycles derivative is killed with sulfur-bearing substituent group 先正达参股股份有限公司 2019-06-14 CN disclosed
CN-109890208-A FUNGICIDAL COMPOSITIONS 先正达参股股份有限公司 2019-06-14 CN disclosed
CN-106488914-B Tool with sulfur-bearing substituent group kills harmful organism active heterocycles derivative 先正达参股股份有限公司 2019-05-14 CN disclosed
CN-106164065-B Harmful organism active heterocycles derivative is killed with sulfur-bearing substituent group 先正达参股股份有限公司 2019-05-10 CN disclosed
CN-106103444-B Microbicidal heterobicyclic derivatives 先正达参股股份有限公司 2019-03-12 CN disclosed
US-4855519-A Method for producing arylethylene NIPPON PETROCHEMICALS COMPANY (JP) 1989-08-08 US disclosed
EP-0316014-A2 Method for producing arylethylenes NIPPON PETROCHEMICALS COMPANY, LIMITED (JP) 1989-05-17 EP disclosed
EP-0281162-A2 Method for improving the electrical insulating characteristics of a fraction, electrical insulating substance, and electrical appliances containing the same NIPPON PETROCHEMICALS COMPANY, LIMITED (JP) 1988-09-07 EP disclosed
US-4681980-A AROMATIC OLEFIN OIL NIPPON PETROCHEMICALS COMPANY LIMITED (JP) 1987-07-21 US disclosed
EP-0115065-A2 Process for preparing oil-containing electrical appliances NIPPON PETROCHEMICALS COMPANY, LIMITED (JP) 1984-08-08 EP disclosed
US-4390194-A DYE-PRECURSOR IN SOLVENT MIXTURE OF 1-METHYL-3-PHENYLINDANE AND A DIARYLALKANE NIPPON PETROCHEMICALS COMPANY, LIMITED (JP) 1983-06-28 US disclosed
US-4347169-A MIXTURE OF A DIARYLALKANE AND AN ARYLINDANE AND-OR 1,3-DIARYLBUTENE NIPPON PETROCHEMICALS COMPANY, LIMITED (JP) 1982-08-31 US disclosed
EP-0000537-B1 INSECTICIDAL AND ACARICIDAL AGENTS, THEIR USE AND METHODS FOR THEIR PREPARATION BAYER AG (DE) 1980-12-10 EP disclosed
US-4022838-A 1,1-DIAR-KETONES, NITRIC ACID, WATER GULF RESEARCH & DEVELOPMENT COMPANY (US) 1977-05-10 US disclosed
US-3978143-A PROCESS FOR PREPARING DIARYLDINITROETHYLENES GULF RESEARCH & DEVELOPMENT COMPANY (US) 1976-08-31 US disclosed