SCHEMBL500599

SCHEMBL500599

c1ccc(OB(c2ccccc2)c2ccc(B(Oc3ccccc3)c3ccccc3)cc2)cc1

nearest known ligand 0.55

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TRPV6 Q9H1D0 4/20 0.55
ORAI1 Q96D31 3/20 0.55
ORAI2 Q96SN7 3/20 0.55
ORAI3 Q9BRQ5 3/20 0.55
CA4 P22748 2/20 0.43
CA1 P00915 2/20 0.43
CA2 P00918 2/20 0.43
TSHR P16473 2/20 0.41
KDM4E B2RXH2 1/20 0.41
MEN1 O00255 1/20 0.41
TRPM2 O94759 1/20 0.41
ALDH1A1 P00352 1/20 0.41
CYP1A2 P05177 1/20 0.41
CYP3A4 P08684 1/20 0.41
THRB P10828 1/20 0.41
HPGD P15428 1/20 0.41
ALOX15 P16050 1/20 0.41
ALOX12 P18054 1/20 0.41
MAPK1 P28482 1/20 0.41
KMT2A Q03164 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4264054 0.97 ORAI1 (0.57) TRPV6ORAI1ORAI2ORAI3CA4
SCHEMBL14187127 0.84 ORAI1 (0.55) TRPV6ORAI1ORAI2ORAI3CA4
SCHEMBL734634 0.76 CA4 (0.46) TRPV6ORAI1ORAI2ORAI3CA4
SCHEMBL2475622 0.72 ORAI1 (0.48) TRPV6ORAI1ORAI2ORAI3CA4
SCHEMBL29113661 0.72 TRPV6 (0.46) TRPV6ORAI1ORAI2ORAI3CA4
SCHEMBL17014985 0.71 LTA4H (0.50) TRPV6ORAI1ORAI2ORAI3CA4
SCHEMBL51246 0.71 LTA4H (0.50) TRPV6ORAI1ORAI2ORAI3CA4
SCHEMBL435243 0.71 TRPV6 (1.00) TRPV6ORAI1ORAI2ORAI3CA4
SCHEMBL14983501 0.70 CA4 (0.58) CA4CA1CA2KDM4EMEN1
Hydrogen Sulfide SCHEMBL16338972 0.69 LTA4H (0.47) TRPV6ORAI1ORAI2ORAI3CA4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8465851-B2 Materials and structures for enhancing the performance of organic light emitting devices UNIVERSAL DISPLAY CORPORATION (US) 2013-06-18 US disclosed
US-20120133276-A1 MATERIALS AND STRUCTURES FOR ENHANCING THE PERFORMANCE OF ORGANIC LIGHT EMITTING DEVICES THOMPSON MARK E (US) 2012-05-31 US disclosed
US-8105700-B2 Materials and structures for enhancing the performance of organic light emitting devices UNIVERSAL DISPLAY CORPORATION (US) 2012-01-31 US disclosed
US-20080309222-A1 Materials and structures for enhancing the performance of organic light emitting devices THOMPSON MARK E 2008-12-18 US disclosed
US-7198859-B2 Materials and structures for enhancing the performance of organic light emitting devices UNIVERSAL DISPLAY CORPORATION (US) 2007-04-03 US disclosed
US-7018723-B2 Materials and structures for enhancing the performance of organic light emitting devices THE UNIVERSITY OF SOUTHERN CALIFORNIA (US) 2006-03-28 US disclosed
US-6902833-B2 Materials and structures for enhancing the performance or organic light emitting devices UNIVERSITY OF SOUTHERN CALIFORNIA (US) 2005-06-07 US disclosed
US-20050025993-A1 Materials and structures for enhancing the performance of organic light emitting devices UNIVERSAL DISPLAY CORPORATION 2005-02-03 US disclosed
US-20050019604-A1 Materials and structures for enhancing the performance of organic light emitting devices UNIVERSAL DISPLAY CORPORATION 2005-01-27 US disclosed
US-20050019605-A1 Materials and structures for enhancing the performance of organic light emitting devices UNIVERSAL DISPLAY CORPORATION 2005-01-27 US disclosed