Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.53 |
| ▸ | PKM | P14618 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.40 |
| ▸ | APBA1 | Q02410 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | CASP1 | P29466 | 2/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL88550 | 0.98 | — | — | |
| Hydrochloric Acid SCHEMBL30310990 | 0.96 | TSHR (0.53) | TSHRPKMSMN1; SMN2CYP3A4ALDH1A1 | |
| Ethylenediamine SCHEMBL7747400 | 0.89 | TSHR (0.55) | TSHRPKMSMN1; SMN2CYP3A4ALDH1A1 | |
| Propionic Acid SCHEMBL11195267 | 0.87 | TSHR (0.54) | TSHRPKMSMN1; SMN2CYP3A4ALDH1A1 | |
| SCHEMBL28545578 | 0.86 | TSHR (0.61) | TSHRPKMSMN1; SMN2CYP3A4ALDH1A1 | |
| Trifluoroacetic Acid SCHEMBL21802650 | 0.85 | TSHR (0.45) | TSHRPKMSMN1; SMN2CYP3A4ALDH1A1 | |
| SCHEMBL1614567 | 0.85 | TSHR (0.61) | TSHRPKMSMN1; SMN2CYP3A4ALDH1A1 | |
| SCHEMBL56403 | 0.84 | TSHR (0.63) | TSHRPKMSMN1; SMN2CYP3A4ALDH1A1 | |
| SCHEMBL15894553 | 0.83 | TSHR (0.65) | TSHRPKMSMN1; SMN2CYP3A4ALDH1A1 | |
| Benzene SCHEMBL28110883 | 0.82 | PKM (0.59) | TSHRPKMSMN1; SMN2CYP3A4ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8105637-B2 | health food and drink contains the pure plant extract, is for patients with abnormality in cerebral blood flow and metabolism of brain disorder; nutraceuticals; free of proanthocyanidins | SHIMADA SHINJI (JP) | 2012-01-31 | — | — | US | disclosed |
| US-20080254126-A1 | Composition comprising nanoparticle ginkgo biloba extract with the effect of brain function activation | SHIMADA SHINJI | 2008-10-16 | — | — | US | disclosed |