SCHEMBL1614567

SCHEMBL1614567

C=CCOC(=O)CCCN

nearest known ligand 0.61

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TSHR P16473 3/20 0.61
CYP1A2 P05177 2/20 0.55
ALDH1A1 P00352 5/20 0.47
GAA P10253 1/20 0.47
PKM P14618 1/20 0.42
SMN1; SMN2 Q16637 1/20 0.42
EPHX2 P34913 1/20 0.41
TDP1 Q9NUW8 1/20 0.40
LMNA P02545 2/20 0.39
NPSR1 Q6W5P4 2/20 0.39
THRB P10828 2/20 0.39
GABRR3 A8MPY1 1/20 0.39
GABRP O00591 1/20 0.39
GABRD O14764 1/20 0.39
HDAC3 O15379 1/20 0.39
GABBR2 O75899 1/20 0.39
GABRA1 P14867 1/20 0.39
GABRB1 P18505 1/20 0.39
GABRG2 P18507 1/20 0.39
GABRR1 P24046 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15894553 0.94 TSHR (0.65) TSHRCYP1A2ALDH1A1GAAPKM
SCHEMBL10349441 0.92 TSHR (0.68) TSHRCYP1A2ALDH1A1GAAPKM
SCHEMBL1012361 0.92 TSHR (0.68) TSHRCYP1A2ALDH1A1GAAPKM
SCHEMBL24809503 0.92 TSHR (0.68) TSHRCYP1A2ALDH1A1GAAPKM
SCHEMBL9003670 0.92 TSHR (0.68) TSHRCYP1A2ALDH1A1GAAPKM
Hydrochloric Acid SCHEMBL29193092 0.90 TSHR (0.66) TSHRCYP1A2ALDH1A1GAAPKM
SCHEMBL88550 0.87
Ethylenediamine SCHEMBL7747400 0.87 TSHR (0.55) TSHRCYP1A2ALDH1A1GAAPKM
SCHEMBL463195 0.87 TSHR (0.70) TSHRCYP1A2ALDH1A1GAAPKM
SCHEMBL153651 0.87 TSHR (0.77) TSHRCYP1A2ALDH1A1GAAPKM

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 58 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3739002-B1 PHOTOVOLTAIC ENCAPSULATION MATERIAL WITH HIGH LIGHT TRANSMITTANCE HANGZHOU FIRST APPLIED MAT CO LTD (CN) 2024-01-17 EP claimed
US-11525043-B2 High light transmittance photovoltaic encapsulating material HANGZHOU FIRST APPLIED MATERIAL CO., LTD. (CN) 2022-12-13 US claimed
US-20210115204-A1 HIGH LIGHT TRANSMITTANCE PHOTOVOLTAIC ENCAPSULATING MATERIAL HANGZHOU FIRST APPLIED MATERIAL CO., LTD. (CN) 2021-04-22 US claimed
EP-3739002-A1 PHOTOVOLTAIC ENCAPSULATION MATERIAL WITH HIGH LIGHT TRANSMITTANCE Hangzhou First Applied Material Co., Ltd. (CN) 2020-11-18 EP claimed
CN-108264682-B A kind of photovoltaic encapsulation material of high transparency 杭州福斯特应用材料股份有限公司 2019-11-15 CN claimed
EP-1753419-B1 Anticancer and antiprotozoal dihydroartemisinin and dihydroartemisitene dimers with desirable chemical functionalities UNIV MISSISSIPPI (US) 2014-01-15 EP claimed
US-7842720-B2 Anticancer and antiprotozoal dihydroartemisinene and dihydroartemisitene dimers with desirable chemical functionalities ELSOHLY LABORATORIES, INCORPORATED (US) 2010-11-30 US claimed
US-20080275106-A1 Anticancer and Antiprotozoal Dihydroartemisinene and Dihydroartemisitene Dimers with Desirable Chemical Functionalities THE UNIVERSITY OF MISSISSIPPI (US) 2008-11-06 US claimed
EP-1753419-A1 ANTICANCER AND ANTIPROTOZOAL DIHYDROARTEMISINENE AND DIHYDROARTEMISITENE DIMERS WITH DESIRABLE CHEMICAL FUNCTIONALITIES University of Mississippi (US) 2007-02-21 EP claimed
WO-2006002105-A1 ANTICANCER AND ANTIPROTOZOAL DIHYDROARTEMISINENE AND DIHYDROARTEMISITENE DIMERS WITH DESIRABLE CHEMICAL FUNCTIONALITIES UNIVERSITY OF MISSISSIPPI (US) 2006-01-05 WO claimed
EP-3274322-B1 STABLE COMPOSITIONS FOR PREVENTION / PROPHYLACTIC TREATMENT OF POISON IVY DERMATITIS THE UNIV OF MISSISSIPPI (US) 2024-08-14 EP disclosed
EP-3739002-B1 PHOTOVOLTAIC ENCAPSULATION MATERIAL WITH HIGH LIGHT TRANSMITTANCE HANGZHOU FIRST APPLIED MAT CO LTD (CN) 2024-01-17 EP disclosed
US-11746114-B2 Thermally sensitive protecting groups for cysteine for peptide cyclization and selective disulfide bond formation UNIVERSITY OF WINDSOR (CA) 2023-09-05 US disclosed
US-11746114-B2 Thermally sensitive protecting groups for cysteine for peptide cyclization and selective disulfide bond formation UNIVERSITY OF WINDSOR (CA) 2023-09-05 US disclosed
US-11746114-B2 Thermally sensitive protecting groups for cysteine for peptide cyclization and selective disulfide bond formation UNIVERSITY OF WINDSOR (CA) 2023-09-05 US disclosed
WO-2006002105-A1 ANTICANCER AND ANTIPROTOZOAL DIHYDROARTEMISINENE AND DIHYDROARTEMISITENE DIMERS WITH DESIRABLE CHEMICAL FUNCTIONALITIES UNIVERSITY OF MISSISSIPPI (US) 2006-01-05 WO disclosed
EP-1416934-A4 PROTEIN KINASE INHIBITORS COMPRISING ATP MIMETICS CONJUGATED TO PEPTIDES OR PEPTIDOMIMETICS PEPTOR LTD (IL) 2005-11-02 EP disclosed
US-20050026840-A1 Protein kinase inhibitors comprising ATP mimetics conjugated to peptides or pertidomimetics CUREGENICS LTD. (IL) 2005-02-03 US disclosed
EP-1416934-A2 PROTEIN KINASE INHIBITORS COMPRISING ATP MIMETICS CONJUGATED TO PEPTIDES OR PEPTIDOMIMETICS Peptor Ltd. (IL) 2004-05-12 EP disclosed
WO-2003010281-A2 PROTEIN KINASE INHIBITORS COMPRISING ATP MIMETICS CONJUGATED TO PEPTIDES OR PEPTIDOMIMETICS PEPTOR LTD. (IL) 2003-02-06 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20080275106-A1 Anticancer and Antiprotozoal Dihydroartemisinene and Dihydroartemisitene Dimers with Desirable Chemical Functionalities DHPS, DHODH, HCCS TSHR 4813/4885CYP1A2 1347/4885ALDH1A1 1448/4885
US-11746114-B2 Thermally sensitive protecting groups for cysteine for peptide cyclization and selective disulfide bond formation PTMS, CTH, VIP TSHR 2842/4885CYP1A2 3756/4885ALDH1A1 351/4885
US-20050026840-A1 Protein kinase inhibitors comprising ATP mimetics conjugated to peptides or pertidomimetics PRKCQ, ADK, PRKCH TSHR 3247/4885CYP1A2 4860/4885ALDH1A1 4840/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.