Dipyridyl

Dipyridyl

SCHEMBL5007665

Cc1ccnc(-c2cc(CCCCBr)ccn2)c1.[Ru].c1ccc(-c2ccccn2)nc1

nearest known ligand 0.45

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CCR1 P32246 2/20 0.45
CCR5 P51681 2/20 0.45
CCR8 P51685 2/20 0.45
SIGMAR1 Q99720 1/20 0.40
FAAH O00519 1/20 0.39
CES1 P23141 1/20 0.39
KDM4E B2RXH2 2/20 0.38
KDM6B O15054 1/20 0.38
KDM4A O75164 1/20 0.38
KDM5C P41229 1/20 0.38
KDM4C Q9H3R0 1/20 0.38
KDM2A Q9Y2K7 1/20 0.38
KDM3A Q9Y4C1 1/20 0.38
KCNN1 Q92952 1/20 0.38
KCNN2 Q9H2S1 1/20 0.38
KCNN3 Q9UGI6 1/20 0.38
SLC2A1 P11166 1/20 0.38
LMNA P02545 1/20 0.37
CYP1A2 P05177 1/20 0.37
POLB P06746 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Dipyridyl SCHEMBL699785 1.00 CCR1 (0.45) CCR1CCR5CCR8SIGMAR1FAAH
Dipyridyl SCHEMBL6503947 0.93 CCR1 (0.41) CCR1CCR5CCR8SIGMAR1FAAH
SCHEMBL17351617 0.92 CCR1 (0.53) CCR1CCR5CCR8SIGMAR1FAAH
Dipyridyl SCHEMBL3126694 0.92 CCR1 (0.40) CCR1CCR5CCR8SIGMAR1FAAH
SCHEMBL30701798 0.90 CCR1 (0.55) CCR1CCR5CCR8SIGMAR1FAAH
SCHEMBL1255405 0.90 CCR1 (0.55) CCR1CCR5CCR8SIGMAR1FAAH
SCHEMBL3031381 0.89 CCR1 (0.53) CCR1CCR5CCR8SIGMAR1FAAH
SCHEMBL2398201 0.89 CCR1 (0.53) CCR1CCR5CCR8SIGMAR1FAAH
SCHEMBL29531413 0.89 CCR1 (0.53) CCR1CCR5CCR8SIGMAR1FAAH
Dipyridyl SCHEMBL701722 0.87 CCR1 (0.45) CCR1CCR5CCR8SIGMAR1FAAH

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 42 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0265519-A4 ELECTROCHEMILUMINESCENT ASSAYS. IGEN INC (US) 1990-05-14 EP claimed
EP-0265519-A1 ELECTROCHEMILUMINESCENT ASSAYS. IGEN INC (US) 1988-05-04 EP claimed
WO-1987006706-A1 ELECTROCHEMILUMINESCENT ASSAYS IGEN, INC. (US) 1987-11-05 WO claimed
EP-2954332-A1 NOVEL LIPOCALIN-MUTEIN ASSAYS FOR MEASURING HEPCIDIN CONCENTRATION Pieris AG (DE) 2015-12-16 EP disclosed
WO-2015187519-A1 TSLP ASSAY MERCK SHARP & DOHME CORP. (US) 2015-12-10 WO disclosed
WO-2014122166-A1 NOVEL LIPOCALIN-MUTEIN ASSAYS FOR MEASURING HEPCIDIN CONCENTRATION PIERIS AG (DE) 2014-08-14 WO disclosed
CN-101547641-A Lateral flow assay device KIMBERLY CLARK CO (US) 2009-09-30 CN disclosed
US-7462322-B2 Methods and apparatus for improved luminescence assays BIOVERIS CORPORATION (US) 2008-12-09 US disclosed
EP-1286164-B1 Methods and apparatus for improved luminescence assays BIOVERIS CORP (US) 2007-07-25 EP disclosed
EP-0885393-B1 GRAPHITIC NANOTUBES IN LUMINESCENCE ASSAYS MESO SCALE TECHNOLOGIES LLC (US) 2007-05-30 EP disclosed
EP-1769243-A2 CROSS-SCREENING SYSTEM AND METHODS FOR DETECTING A MOLECULE HAVING BINDING AFFINITY FOR A TARGET MOLECULE Genentech, Inc. (US) 2007-04-04 EP disclosed
EP-0570518-A1 METHODS AND APPARATUS FOR IMPROVED ELECTROCHEMI LUMINESCENCE ASSAYS IGEN, INC. (US) 1993-11-24 EP disclosed
EP-0441894-A4 ELECTROCHEMILUMINESCENT REACTION UTILIZING AMINE-DERIVED REDUCTANT 1992-09-16 EP disclosed
WO-1992014139-A1 METHODS AND APPARATUS FOR IMPROVED LUMINESCENCE ASSAYS IGEN, INC. (US) 1992-08-20 WO disclosed
WO-1992014138-A1 METHOD AND APPARATUS FOR MAGNETIC MICROPARTICULATE BASED LUMINESCENCE ASSAY INCLUDING PLURALITY OF MAGNETS IGEN, INC. (US) 1992-08-20 WO disclosed
EP-0441894-A1 ELECTROCHEMILUMINESCENT REACTION UTILIZING AMINE-DERIVED REDUCTANT IGEN, INC. (US) 1991-08-21 EP disclosed
WO-1990005296-A1 ELECTROCHEMILUMINESCENT REACTION UTILIZING AMINE-DERIVED REDUCTANT IGEN, INC. (US) 1990-05-17 WO disclosed
EP-0265519-A4 ELECTROCHEMILUMINESCENT ASSAYS. IGEN INC (US) 1990-05-14 EP disclosed
EP-0265519-A1 ELECTROCHEMILUMINESCENT ASSAYS. IGEN INC (US) 1988-05-04 EP disclosed
WO-1987006706-A1 ELECTROCHEMILUMINESCENT ASSAYS IGEN, INC. (US) 1987-11-05 WO disclosed