Dipyridyl

Dipyridyl

SCHEMBL6503947

Cc1ccnc(-c2cc(CCCCBr)ccn2)c1.[O-][Cl+3]([O-])([O-])[O-].[O-][Cl+3]([O-])([O-])[O-].[Ru+2].c1ccc(-c2ccccn2)nc1.c1ccc(-c2ccccn2)nc1

nearest known ligand 0.41

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CCR1 P32246 2/20 0.41
CCR5 P51681 2/20 0.41
CCR8 P51685 2/20 0.41
SIGMAR1 Q99720 1/20 0.38
FAAH O00519 1/20 0.37
CES1 P23141 1/20 0.37
KCNN1 Q92952 1/20 0.36
KCNN2 Q9H2S1 1/20 0.36
KCNN3 Q9UGI6 1/20 0.36
KDM4E B2RXH2 2/20 0.35
KDM6B O15054 1/20 0.35
KDM4A O75164 1/20 0.35
KDM5C P41229 1/20 0.35
KDM4C Q9H3R0 1/20 0.35
KDM2A Q9Y2K7 1/20 0.35
KDM3A Q9Y4C1 1/20 0.35
SLC2A1 P11166 1/20 0.35
GRM5 P41594 1/20 0.34
DCTPP1 Q9H773 1/20 0.34
LMNA P02545 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Dipyridyl SCHEMBL699785 0.93 CCR1 (0.45) CCR1CCR5CCR8SIGMAR1FAAH
Dipyridyl SCHEMBL5007665 0.93 CCR1 (0.45) CCR1CCR5CCR8SIGMAR1FAAH
Dipyridyl SCHEMBL3126694 0.89 CCR1 (0.40) CCR1CCR5CCR8SIGMAR1FAAH
SCHEMBL29531413 0.87 CCR1 (0.53) CCR1CCR5CCR8SIGMAR1FAAH
SCHEMBL1255405 0.86 CCR1 (0.55) CCR1CCR5CCR8SIGMAR1FAAH
SCHEMBL30701798 0.86 CCR1 (0.55) CCR1CCR5CCR8SIGMAR1FAAH
SCHEMBL2398201 0.85 CCR1 (0.53) CCR1CCR5CCR8SIGMAR1FAAH
SCHEMBL17351617 0.85 CCR1 (0.53) CCR1CCR5CCR8SIGMAR1FAAH
SCHEMBL3031381 0.85 CCR1 (0.53) CCR1CCR5CCR8SIGMAR1FAAH
Dipyridyl SCHEMBL1318097 0.81 CCR1 (0.46) CCR1CCR5CCR8SIGMAR1FAAH

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6916606-B2 Electrochemiluminescent assays BIOVERIS CORPORATION (US) 2005-07-12 US disclosed
US-20050106652-A1 Detecting coliform bacteria in food liquids and/or homogenates; immunoassay BIOVERIS CORPORATION 2005-05-19 US disclosed
EP-0658564-B1 Electroluminescent compounds and intermediates in their synthesis IGEN INT INC (US) 2002-01-16 EP disclosed
US-6316607-B1 AS LABLES IN DETECTING AND QUANTIFYING CHEMICAL, BIOCHEMICAL, AND BIOLOGICAL SUBSTANCES, DRUGS, METABOLITES, MICROORGANISMS IGEN INTERNATIONAL, INC. 2001-11-13 US disclosed
EP-0265519-B1 ELECTROCHEMILUMINESCENT ASSAYS IGEN INC (US) 1995-09-13 EP disclosed
EP-0658564-A1 Electroluminescent compounds and intermediates in their synthesis IGEN, INC. (US) 1995-06-21 EP disclosed
EP-0647849-A2 Detecting the presence of analytes in a sample IGEN, INC. (US) 1995-04-12 EP disclosed
EP-0265519-A4 ELECTROCHEMILUMINESCENT ASSAYS. IGEN INC (US) 1990-05-14 EP disclosed
EP-0265519-A1 ELECTROCHEMILUMINESCENT ASSAYS. IGEN INC (US) 1988-05-04 EP disclosed
WO-1987006706-A1 ELECTROCHEMILUMINESCENT ASSAYS IGEN, INC. (US) 1987-11-05 WO disclosed