Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCR1 | P32246 | 2/20 | 0.45 |
| ▸ | CCR5 | P51681 | 2/20 | 0.45 |
| ▸ | CCR8 | P51685 | 2/20 | 0.45 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.40 |
| ▸ | FAAH | O00519 | 1/20 | 0.39 |
| ▸ | CES1 | P23141 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.38 |
| ▸ | KDM6B | O15054 | 1/20 | 0.38 |
| ▸ | KDM4A | O75164 | 1/20 | 0.38 |
| ▸ | KDM5C | P41229 | 1/20 | 0.38 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.38 |
| ▸ | KDM2A | Q9Y2K7 | 1/20 | 0.38 |
| ▸ | KDM3A | Q9Y4C1 | 1/20 | 0.38 |
| ▸ | KCNN1 | Q92952 | 1/20 | 0.38 |
| ▸ | KCNN2 | Q9H2S1 | 1/20 | 0.38 |
| ▸ | KCNN3 | Q9UGI6 | 1/20 | 0.38 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Dipyridyl SCHEMBL5007665 | 1.00 | CCR1 (0.45) | CCR1CCR5CCR8SIGMAR1FAAH | |
| Dipyridyl SCHEMBL6503947 | 0.93 | CCR1 (0.41) | CCR1CCR5CCR8SIGMAR1FAAH | |
| SCHEMBL17351617 | 0.92 | CCR1 (0.53) | CCR1CCR5CCR8SIGMAR1FAAH | |
| Dipyridyl SCHEMBL3126694 | 0.92 | CCR1 (0.40) | CCR1CCR5CCR8SIGMAR1FAAH | |
| SCHEMBL30701798 | 0.90 | CCR1 (0.55) | CCR1CCR5CCR8SIGMAR1FAAH | |
| SCHEMBL1255405 | 0.90 | CCR1 (0.55) | CCR1CCR5CCR8SIGMAR1FAAH | |
| SCHEMBL3031381 | 0.89 | CCR1 (0.53) | CCR1CCR5CCR8SIGMAR1FAAH | |
| SCHEMBL2398201 | 0.89 | CCR1 (0.53) | CCR1CCR5CCR8SIGMAR1FAAH | |
| SCHEMBL29531413 | 0.89 | CCR1 (0.53) | CCR1CCR5CCR8SIGMAR1FAAH | |
| Dipyridyl SCHEMBL701722 | 0.87 | CCR1 (0.45) | CCR1CCR5CCR8SIGMAR1FAAH |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 177 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7247375-B2 | Polymeric matrices for the encapsulation of phosphorescent molecules for analytical applications | KIMBERLY-CLARK WORLDWIDE, INC. (US) | 2007-07-24 | — | — | US | claimed |
| WO-2005111174-A1 | POLYMERIC MATRICES FOR THE ENCAPSULATION OF PHOSPHORESCENT MOLECULES FOR ANALYTICAL APPLICATIONS | KIMBERLY-CLARK WORLDWIDE, INC. (US) | 2005-11-24 | — | — | WO | claimed |
| US-20050244643-A1 | Polymeric matrices for the encapsulation of phosphorescent molecules for analytical applications | KIMBERLY-CLARK WORLDWIDE, INC. | 2005-11-03 | — | — | US | claimed |
| US-6132955-A | Method for derivitizing electrodes and assay methods using such derivitized electrodes | IGEN INTERNATIONAL, INC. (US) | 2000-10-17 | — | — | US | claimed |
| EP-0265519-B1 | ELECTROCHEMILUMINESCENT ASSAYS | IGEN INC (US) | 1995-09-13 | — | — | EP | claimed |
| EP-0265519-A4 | ELECTROCHEMILUMINESCENT ASSAYS. | IGEN INC (US) | 1990-05-14 | — | — | EP | claimed |
| EP-0265519-A1 | ELECTROCHEMILUMINESCENT ASSAYS. | IGEN INC (US) | 1988-05-04 | — | — | EP | claimed |
| WO-1987006706-A1 | ELECTROCHEMILUMINESCENT ASSAYS | IGEN, INC. (US) | 1987-11-05 | — | — | WO | claimed |
| US-20240201190-A1 | COMPOSITIONS AND METHODS OF DIAGNOSING PANCREATIC CANCER | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2024-06-20 | — | — | US | disclosed |
| US-20230174912-A1 | SYSTEM, DEVICE, AND METHOD FOR SINGLE-CELL ENCAPSULATION AND CULTURE | UNIVERSITY OF MARYLAND, COLLEGE PARK | 2023-06-08 | — | — | US | disclosed |
| US-11112409-B2 | Systems and compositions for diagnosing pathogenic fungal infection and methods of using the same | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2021-09-07 | — | — | US | disclosed |
| US-20210123923-A1 | METHODS OF MONITORING, TREATING, AND PREVENTING RENAL INFLAMMATION ASSOCIATED WITH NEPHROTOXICITY | KANTUM PHARMA, INC. | 2021-04-29 | — | — | US | disclosed |
| US-20210121451-A1 | METHODS OF MONITORING, TREATING, AND PREVENTING RENAL INFLAMMATION ASSOCIATED WITH KIDNEY TRANSPLANTATION | KANTUM PHARMA, INC. | 2021-04-29 | — | — | US | disclosed |
| US-20210113543-A1 | METHODS OF MONITORING, TREATING, AND PREVENTING RENAL INFLAMMATION FOLLOWING CARDIAC PROCEDURES OR EVENTS | KANTUM PHARMA, INC. | 2021-04-22 | — | — | US | disclosed |
| US-5705402-A | COMPLEXING | IGEN INTERNATIONAL, INC. (US) | 1998-01-06 | — | — | US | disclosed |
| WO-1996015440-A1 | MAGNETIC PARTICLE BASED ELECTROCHEMILUMINESCENT DETECTION APPARATUS AND METHOD | IGEN, INC. (US) | 1996-05-23 | — | — | WO | disclosed |
| EP-0265519-B1 | ELECTROCHEMILUMINESCENT ASSAYS | IGEN INC (US) | 1995-09-13 | — | — | EP | disclosed |
| EP-0658564-A1 | Electroluminescent compounds and intermediates in their synthesis | IGEN, INC. (US) | 1995-06-21 | — | — | EP | disclosed |
| EP-0647849-A2 | Detecting the presence of analytes in a sample | IGEN, INC. (US) | 1995-04-12 | — | — | EP | disclosed |
| US-4939140-A | ALDOSE REDUCTASE INHIBITORS | PFIZER INC. (US) | 1990-07-03 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210113543-A1 | METHODS OF MONITORING, TREATING, AND PREVENTING RENAL INFLAMMATION FOLLOWING CARDIAC PROCEDURES OR EVENTS | P2RY14, FUT5, GALNT14 | CCR1 1678/4885CCR5 345/4885CCR8 1849/4885 |
| US-20210123923-A1 | METHODS OF MONITORING, TREATING, AND PREVENTING RENAL INFLAMMATION ASSOCIATED WITH NEPHROTOXICITY | P2RY14, P2RY12, P2RY1 | CCR1 1252/4885CCR5 336/4885CCR8 1664/4885 |
| US-20210121451-A1 | METHODS OF MONITORING, TREATING, AND PREVENTING RENAL INFLAMMATION ASSOCIATED WITH KIDNEY TRANSPLANTATION | P2RY14, P2RY12, P2RY13 | CCR1 1597/4885CCR5 368/4885CCR8 1282/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.