Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPV4 | Q9HBA0 | 2/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | ACKR3 | P25106 | 2/20 | 0.44 |
| ▸ | OPRM1 | P35372 | 3/20 | 0.43 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.42 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.42 |
| ▸ | DRD3 | P35462 | 5/20 | 0.42 |
| ▸ | DRD2 | P14416 | 5/20 | 0.42 |
| ▸ | HTR1A | P08908 | 3/20 | 0.42 |
| ▸ | HTR2A | P28223 | 3/20 | 0.42 |
| ▸ | RAB9A | P51151 | 2/20 | 0.40 |
| ▸ | DRD1 | P21728 | 2/20 | 0.39 |
| ▸ | DRD4 | P21917 | 1/20 | 0.39 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.39 |
| ▸ | HTR2C | P28335 | 1/20 | 0.39 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.39 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.39 |
| ▸ | HTR2B | P41595 | 1/20 | 0.39 |
| ▸ | CCR1 | P32246 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5011594 | 0.89 | TRPV4 (0.54) | TRPV4ACKR3OPRM1SLC6A2SLC6A4 | |
| SCHEMBL5004473 | 0.87 | TRPV4 (0.54) | TRPV4ACKR3OPRM1SLC6A2SLC6A4 | |
| SCHEMBL5007939 | 0.85 | TRPV4 (0.60) | TRPV4ACKR3OPRM1SLC6A2SLC6A4 | |
| SCHEMBL5007235 | 0.85 | TRPV4 (0.48) | TRPV4ACKR3OPRM1SLC6A2SLC6A4 | |
| SCHEMBL5007951 | 0.85 | TRPV4 (0.48) | TRPV4ACKR3OPRM1SLC6A2SLC6A4 | |
| SCHEMBL5007972 | 0.85 | TRPV4 (0.54) | TRPV4ACKR3SLC6A2SLC6A4DRD3 | |
| SCHEMBL5004501 | 0.83 | TRPV4 (0.72) | TRPV4ACKR3OPRM1SLC6A2SLC6A4 | |
| SCHEMBL5007925 | 0.83 | TRPV4 (0.58) | TRPV4ACKR3OPRM1SLC6A2SLC6A4 | |
| SCHEMBL5007269 | 0.83 | TRPV4 (0.46) | TRPV4ACKR3OPRM1SLC6A2SLC6A4 | |
| SCHEMBL4972091 | 0.83 | TRPV4 (0.74) | TRPV4ALDH1A1ACKR3OPRM1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080318945-A1 | Novel Compounds | CASILLAS LINDA N | 2008-12-25 | — | — | US | claimed |
| US-20080318945-A1 | Novel Compounds | CASILLAS LINDA N | 2008-12-25 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080318945-A1 | Novel Compounds | TRPV4, TRPV1, TRPV3 | TRPV4 1/4885ALDH1A1 2369/4885ACKR3 217/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.