Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DHODH | Q02127 | 14/20 | 0.46 |
| ▸ | ADORA1 | P30542 | 5/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5012051 | 0.89 | METAP2 (0.44) | DHODHADORA1MAPT | |
| SCHEMBL5005493 | 0.89 | ADORA1 (0.60) | DHODHADORA1MAPT | |
| SCHEMBL5008441 | 0.86 | MAPT (0.47) | ADORA1MAPT | |
| SCHEMBL5005236 | 0.85 | ADORA1 (0.56) | DHODHADORA1MAPT | |
| SCHEMBL5008775 | 0.83 | ADORA1 (0.55) | DHODHADORA1MAPT | |
| SCHEMBL5008323 | 0.82 | ADORA1 (0.54) | ADORA1MAPT | |
| SCHEMBL3979001 | 0.82 | MAPT (0.39) | ADORA1MAPT | |
| SCHEMBL3975682 | 0.82 | MAPT (0.41) | DHODHADORA1MAPT | |
| SCHEMBL5010620 | 0.81 | MAPT (0.51) | DHODHADORA1MAPT | |
| SCHEMBL5008457 | 0.81 | ADORA1 (0.47) | ADORA1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080064734-A1 | Anilinopyrazole derivatives useful for the treatment of diabetes | BAYER PHARMACEUTICALS CORPORATION (US) | 2008-03-13 | — | — | US | disclosed |
| US-7265144-B2 | Anilinopyrazole derivatives useful for the treatment of diabetes | BAYER PHARMACEUTICALS CORPORATION (US) | 2007-09-04 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080064734-A1 | Anilinopyrazole derivatives useful for the treatment of diabetes | IAPP, GLP1R, GPR119 | DHODH 2978/4885ADORA1 749/4885MAPT 2420/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.