SCHEMBL5008540

SCHEMBL5008540

CC(C)(C)c1cc(CCC(=O)OC2CC(C)(C)N(CCOC(=O)CCc3cc(C(C)(C)C)c(O)c(C(C)(C)C)c3)C(C)(C)C2)c(O)c(C(C)(C)C)c1

nearest known ligand 0.40

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 2/20 0.37
MEN1 O00255 1/20 0.37
GAA P10253 5/20 0.35
HTT P42858 2/20 0.34
PKM P14618 1/20 0.34
ALDH1A1 P00352 2/20 0.33
XBP1 P17861 1/20 0.33
MAPK1 P28482 1/20 0.33
NPSR1 Q6W5P4 1/20 0.33
MAOB P27338 3/20 0.33
MAOA P21397 2/20 0.33
ACHE P22303 1/20 0.32
ALOX5 P09917 1/20 0.31
KDM4E B2RXH2 1/20 0.30
MAPT P10636 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4302639 1.00 KMT2A (0.37) KMT2AMEN1GAAHTTPKM
SCHEMBL27938272 0.96 GAA (0.35) KMT2AMEN1GAAHTTPKM
SCHEMBL206978 0.92 KMT2A (0.43) KMT2AMEN1GAAHTTPKM
SCHEMBL17866245 0.90 KMT2A (0.38) KMT2AMEN1GAAHTTPKM
SCHEMBL5415495 0.87 GAA (0.37) KMT2AMEN1GAAHTTPKM
SCHEMBL2958675 0.86 ALOX5 (0.44) KMT2AMEN1GAAHTTPKM
SCHEMBL2998267 0.86 APP (0.40) KMT2AMEN1GAAHTTPKM
SCHEMBL4183571 0.85 GAA (0.35) GAAHTTPKMALDH1A1XBP1
SCHEMBL28146882 0.83 GAA (0.38) KMT2AMEN1GAAHTTPKM
SCHEMBL28173021 0.83 KMT2A (0.35) KMT2AMEN1GAAHTTPKM

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20080285144-A1 Optical Element ZEON CORPORATION (JP) 2008-11-20 US disclosed
EP-1830219-A1 OPTICAL DEVICE ZEON CORPORATION (JP) 2007-09-05 EP disclosed
US-20060199015-A1 Resin composition and transparent shaped article ZEON CORPORATION (JP) 2006-09-07 US disclosed
CN-1764697-A Resin composition and transparent molded article ZEON CORP (JP) 2006-04-26 CN disclosed
EP-1612245-A1 RESIN COMPOSITION AND TRANSPARENT FORMED ARTICLE ZEON CORPORATION (JP) 2006-01-04 EP disclosed