SCHEMBL5008762

SCHEMBL5008762

C=CCOC(O)(CC)C(=C)C(=O)O

nearest known ligand 0.32

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
TSHR P16473 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Methacrylic Acid SCHEMBL10799545 0.75 TSHR (0.32) TSHR
SCHEMBL9512602 0.69 ALDH1A1 (0.32) TSHR
SCHEMBL2144019 0.69 TSHR (0.30) TSHR
SCHEMBL10521805 0.68 TSHR (0.34) TSHR
SCHEMBL2142744 0.68
SCHEMBL3417372 0.68 TSHR (0.31) TSHR
SCHEMBL28178492 0.67 TSHR (0.36) TSHR
SCHEMBL5012061 0.66 THRB (0.33) TSHR
SCHEMBL11198239 0.65 TET2 (0.38) TSHR
SCHEMBL13372797 0.65 TET2 (0.38) TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1963402-A2 PROCESS FOR THE PRODUCTION OF MONODISPERSE AND NARROW DISPERSE MONOFUNCTIONAL SILICONES Johnson and Johnson Vision Care, Inc. (US) 2008-09-03 EP claimed
US-20060229423-A1 Process for the production of monodisperse and narrow disperse monofunctional silicones JOHNSON & JOHNSON VISION CARE, INC. 2006-10-12 US claimed
WO-2006102050-A2 PROCESS FOR THE PRODUCTION OF MONODISPERSE AND NARROW DISPERSE MONOFUNCTIONAL SILICONES JOHNSON & JOHNSON VISION CARE, INC. (US) 2006-09-28 WO claimed
EP-1963402-A2 PROCESS FOR THE PRODUCTION OF MONODISPERSE AND NARROW DISPERSE MONOFUNCTIONAL SILICONES Johnson and Johnson Vision Care, Inc. (US) 2008-09-03 EP disclosed
US-20060229423-A1 Process for the production of monodisperse and narrow disperse monofunctional silicones JOHNSON & JOHNSON VISION CARE, INC. 2006-10-12 US disclosed
WO-2006102050-A2 PROCESS FOR THE PRODUCTION OF MONODISPERSE AND NARROW DISPERSE MONOFUNCTIONAL SILICONES JOHNSON & JOHNSON VISION CARE, INC. (US) 2006-09-28 WO disclosed