SCHEMBL5008908

SCHEMBL5008908

CCC[C](c1ccccc1-c1ccccc1)c1ccccc1-c1ccccc1

nearest known ligand 0.47

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 2/20 0.47
KMT2A Q03164 2/20 0.47
SMN1; SMN2 Q16637 2/20 0.47
BCAT2 O15382 1/20 0.47
LTB4R2 Q9NPC1 3/20 0.44
ALDH1A1 P00352 2/20 0.44
SCN1A P35498 3/20 0.43
SCN2A Q99250 3/20 0.43
SCN3A Q9NY46 3/20 0.43
HPGD P15428 2/20 0.43
L3MBTL1 Q9Y468 1/20 0.43
CNR1 P21554 1/20 0.43
CNR2 P34972 1/20 0.43
CHRNB2 P17787 2/20 0.42
CHRNB4 P30926 2/20 0.42
CHRNA3 P32297 2/20 0.42
CHRNA4 P43681 2/20 0.42
LMNA P02545 1/20 0.42
SOAT1 P35610 2/20 0.41
BCL2L1 Q07817 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5008902 0.85 HNF4A (0.43) MEN1KMT2ASMN1; SMN2BCAT2LTB4R2
SCHEMBL5008829 0.83 SMN1; SMN2 (0.50) MEN1KMT2ASMN1; SMN2BCAT2LTB4R2
SCHEMBL3630027 0.81 SMN1; SMN2 (0.58) MEN1KMT2ASMN1; SMN2BCAT2LTB4R2
SCHEMBL30522208 0.74 LTB4R2 (0.55) MEN1KMT2ASMN1; SMN2BCAT2LTB4R2
SCHEMBL8148053 0.74 LTB4R2 (0.55) MEN1KMT2ASMN1; SMN2BCAT2LTB4R2
SCHEMBL5008824 0.73 CHRNB2 (0.51) MEN1KMT2ASMN1; SMN2BCAT2LTB4R2
Butyric Acid SCHEMBL29482175 0.73 FFAR3 (0.54) MEN1KMT2ASMN1; SMN2BCAT2ALDH1A1
SCHEMBL6025886 0.73 MEN1 (0.48) MEN1KMT2ASMN1; SMN2BCAT2LTB4R2
SCHEMBL10775382 0.73 POLB (0.52) LTB4R2ALDH1A1HPGDL3MBTL1CHRNB2
SCHEMBL11484301 0.73 MEN1 (0.45) MEN1KMT2ASMN1; SMN2BCAT2LTB4R2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20080207864-A1 Organosilanes, Process For Production of the Same, and Use Thereof SHARP KABUSHIKI KAISHA (JP) 2008-08-28 US disclosed