Methacrylic Acid

Methacrylic Acid

SCHEMBL5008920

C=C(C)C(=O)O.C=C(C)C(=O)OC.C=C(C)C(=O)OCc1ccccc1.C=CC(=O)OCC(CC)CCCC

nearest known ligand 0.55

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TSHR P16473 4/20 0.55
ALDH1A1 P00352 7/20 0.44
CYP3A4 P08684 4/20 0.44
CA2 P00918 1/20 0.44
TDP1 Q9NUW8 3/20 0.42
MAPK1 P28482 4/20 0.42
LMNA P02545 3/20 0.42
PRSS1 P07477 1/20 0.40
PRSS2 P07478 1/20 0.40
PRSS3 P35030 1/20 0.40
MBOAT4 Q96T53 1/20 0.38
CTSL P07711 1/20 0.37
CTSS P25774 1/20 0.37
HSD17B10 Q99714 1/20 0.36
ATM Q13315 1/20 0.36
MEN1 O00255 1/20 0.35
HPGD P15428 1/20 0.35
KMT2A Q03164 1/20 0.35
L3MBTL1 Q9Y468 1/20 0.35
TGM2 P21980 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6263639 0.98 TSHR (0.57) TSHRALDH1A1CYP3A4CA2TDP1
SCHEMBL15529137 0.90 TSHR (0.47) TSHRALDH1A1CYP3A4CA2TDP1
Styrene SCHEMBL7760829 0.89 TSHR (0.57) TSHRALDH1A1CYP3A4CA2TDP1
Methacrylic Acid SCHEMBL8956686 0.88 TSHR (0.71) TSHRALDH1A1CYP3A4CA2TDP1
Acrylic Acid SCHEMBL5492279 0.87 ALDH1A1 (0.50) TSHRALDH1A1CYP3A4CA2TDP1
Styrene SCHEMBL2352031 0.86 TSHR (0.59) TSHRALDH1A1CYP3A4CA2TDP1
Styrene SCHEMBL1091500 0.86 TSHR (0.52) TSHRALDH1A1CYP3A4CA2TDP1
SCHEMBL31365383 0.86 TSHR (0.71) TSHRALDH1A1CYP3A4CA2TDP1
SCHEMBL1931959 0.85 TSHR (0.76) TSHRALDH1A1CYP3A4CA2TDP1
SCHEMBL29141898 0.85 TSHR (0.76) TSHRALDH1A1CYP3A4CA2TDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7435531-B2 Multilayer coatings of thermoplastic resins and photosensitive resins on thin films of polyethylene terephthalate as supports, for use as color filters for liquid crystal displays FUJIFILM CORPORATION (JP) 2008-10-14 US disclosed
WO-2005091078-A1 PATTERN FORMING PROCESS AND PATTERN FUJI PHOTO FILM CO., LTD. (JP) 2005-09-29 WO disclosed
WO-2005078776-A1 PATTERN FORMING PROCESS FUJI PHOTO FILM CO., LTD. (JP) 2005-08-25 WO disclosed
US-20030215743-A1 Multilayer coatings of thermoplastic resins and photosensitive resins on thin films of polyethylene terephthalate as supports, for use as color filters for liquid crystal displays FUJIFILM CORPORATION (JP) 2003-11-20 US disclosed