Styrene

Styrene

SCHEMBL7760829

C=C(C)C(=O)O.C=C(C)C(=O)OC.C=CC(=O)OCC(CC)CCCC.C=Cc1ccccc1

nearest known ligand 0.57

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TSHR P16473 5/20 0.57
TDP1 Q9NUW8 3/20 0.46
ALDH1A1 P00352 6/20 0.46
CYP3A4 P08684 3/20 0.46
CA2 P00918 1/20 0.46
LMNA P02545 3/20 0.43
MAPK1 P28482 3/20 0.43
PRSS1 P07477 1/20 0.42
PRSS2 P07478 1/20 0.42
PRSS3 P35030 1/20 0.42
HSD17B10 Q99714 1/20 0.38
ATM Q13315 1/20 0.37
KDM4E B2RXH2 1/20 0.35
TAS1R3 Q7RTX0 1/20 0.34
TAS1R1 Q7RTX1 1/20 0.34
RECQL P46063 1/20 0.33
HPGD P15428 1/20 0.33
MEN1 O00255 1/20 0.32
MAPT P10636 1/20 0.32
KMT2A Q03164 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Styrene SCHEMBL2352031 0.98 TSHR (0.59) TSHRTDP1ALDH1A1CYP3A4CA2
Styrene SCHEMBL5952124 0.96 TSHR (0.57) TSHRTDP1ALDH1A1CYP3A4CA2
Styrene SCHEMBL1091500 0.95 TSHR (0.52) TSHRTDP1ALDH1A1CYP3A4CA2
Styrene SCHEMBL7716318 0.94 TSHR (0.55) TSHRTDP1ALDH1A1CYP3A4CA2
Styrene SCHEMBL27467831 0.94 TSHR (0.64) TSHRTDP1ALDH1A1CYP3A4CA2
Styrene SCHEMBL27965587 0.94 TSHR (0.49) TSHRTDP1ALDH1A1CYP3A4CA2
Styrene SCHEMBL9510287 0.93 TSHR (0.53) TSHRTDP1ALDH1A1CYP3A4CA2
Styrene SCHEMBL29157682 0.91 TSHR (0.60) TSHRTDP1ALDH1A1CYP3A4CA2
Styrene SCHEMBL28988056 0.91 ALDH1A1 (0.50) TSHRTDP1ALDH1A1CYP3A4CA2
Styrene SCHEMBL1765871 0.90 TSHR (0.57) TSHRTDP1ALDH1A1CYP3A4CA2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0770910-B1 Image forming method FUJI PHOTO FILM CO LTD (JP) 2001-05-16 EP disclosed
US-5736293-A USING MIXTURES OF 1-PHENYL-3-PYRAZOLIDONES AND CATECHOLS(AND DERIVATIVES) AS REDUCING AGENTS IN HEAT DEVELOPMENT OF A LAMINATED PHOTOSENSITIVE SHEET YIELDS HIGH DENSITY IMAGES HAVING LOW FOGGING, GOOD HALFTONES AND HIGH CONTRAST FUJI PHOTO FILM CO., LTD. (JP) 1998-04-07 US disclosed
EP-0770910-A1 Image forming method FUJI PHOTO FILM CO., LTD. (JP) 1997-05-02 EP disclosed