Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A4 | P31645 | 8/20 | 0.68 |
| ▸ | HTR1A | P08908 | 2/20 | 0.68 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.68 |
| ▸ | LMNA | P02545 | 1/20 | 0.68 |
| ▸ | POLB | P06746 | 1/20 | 0.68 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.68 |
| ▸ | HTR6 | P50406 | 1/20 | 0.68 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.68 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.68 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Fumaric Acid SCHEMBL10674120 | 0.89 | SLC6A4 (0.56) | SLC6A4HTR1AKDM4ELMNAPOLB | |
| SCHEMBL10671532 | 0.83 | HTR1A (0.59) | SLC6A4HTR1AKDM4ELMNAPOLB | |
| SCHEMBL10674565 | 0.82 | KDM4E (0.70) | SLC6A4HTR1AKDM4ELMNAPOLB | |
| Hydrochloric Acid SCHEMBL11439099 | 0.81 | SLC6A4 (1.00) | SLC6A4HTR1AKDM4ELMNAPOLB | |
| SCHEMBL4674658 | 0.81 | SLC6A4 (1.00) | SLC6A4HTR1AKDM4ELMNAPOLB | |
| SCHEMBL10672260 | 0.81 | HTR1A (0.57) | SLC6A4HTR1AKDM4ELMNAALOX15 | |
| SCHEMBL20740133 | 0.79 | MAPT (0.47) | SLC6A4HTR1AKDM4ELMNAPOLB | |
| SCHEMBL11228410 | 0.78 | HTR2A (0.54) | HTR6 | |
| SCHEMBL7648302 | 0.78 | MAPT (0.53) | SLC6A4HTR1AKDM4ELMNAPOLB | |
| SCHEMBL3673755 | 0.78 | SLC6A4 (0.54) | SLC6A4HTR1AKDM4ELMNAPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080318941-A1 | 4' SUBSTITUTED COMPOUNDS HAVING 5-HT6 RECEPTOR AFFINITY | MEMORY PHARMACEUTICALS CORPORATION (US) | 2008-12-25 | — | — | US | disclosed |
| US-4737505-A | Analgesic 4-substituted indoles | ROUSSEL UCLAF (FR) | 1988-04-12 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080318941-A1 | 4' SUBSTITUTED COMPOUNDS HAVING 5-HT6 RECEPTOR AFFINITY | HTR6, HTR1B, HTR3B | SLC6A4 19/4885HTR1A 5/4885KDM4E 1481/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.