SCHEMBL5009155

SCHEMBL5009155

CCCCOc1c(C=C2N(CCCCCC(=O)O)c3ccccc3C2(C)C)c(=O)c1=O

nearest known ligand 0.38

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 5/20 0.38
FOLH1 Q04609 1/20 0.38
MEN1 O00255 3/20 0.37
MAPT P10636 3/20 0.37
KMT2A Q03164 3/20 0.37
SMN1; SMN2 Q16637 2/20 0.37
GPR55 Q9Y2T6 2/20 0.37
GLA P06280 1/20 0.37
HTT P42858 1/20 0.37
OPRL1 P41146 1/20 0.37
CDC25A P30304 10/20 0.36
KDM4E B2RXH2 1/20 0.36
MAPK1 P28482 1/20 0.36
NPSR1 Q6W5P4 1/20 0.36
L3MBTL1 Q9Y468 1/20 0.36
PLA2G4B P0C869 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19815097 0.92 KMT2A (0.41) ALDH1A1MEN1MAPTKMT2ASMN1; SMN2
SCHEMBL21314805 0.92 KMT2A (0.41) ALDH1A1MEN1MAPTKMT2ASMN1; SMN2
SCHEMBL17627888 0.86 ALDH1A1 (0.40) ALDH1A1MEN1MAPTKMT2ASMN1; SMN2
SCHEMBL6234350 0.86 S1PR3 (0.36) ALDH1A1FOLH1MEN1MAPTKMT2A
SCHEMBL13103144 0.85 ALDH1A1 (0.38) ALDH1A1MEN1MAPTKMT2ASMN1; SMN2
SCHEMBL7745679 0.84 ALDH1A1 (0.46) ALDH1A1MEN1MAPTKMT2ASMN1; SMN2
SCHEMBL7750488 0.84 ALDH1A1 (0.46) ALDH1A1MEN1MAPTKMT2ASMN1; SMN2
SCHEMBL16328778 0.84 KMT2A (0.39) ALDH1A1MEN1MAPTKMT2ASMN1; SMN2
SCHEMBL19815786 0.83 MAPT (0.48) ALDH1A1MEN1MAPTKMT2ASMN1; SMN2
SCHEMBL5515255 0.83 MAPT (0.48) ALDH1A1MEN1MAPTKMT2ASMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9841428-B2 Viscosity-sensitive dyes and method SETA BIOMEDICALS, LLC (US) 2017-12-12 US disclosed
US-20160091495-A1 VISCOSITY-SENSITIVE DYES AND METHOD SETA BIOMEDICALS, LLC 2016-03-31 US disclosed
US-7411068-B2 Luminescent compounds SETA BIOMEDICALS, LLC 2008-08-12 US disclosed
US-20050202565-A1 Luminescent compounds SETA BIOMEDICALS, LLC 2005-09-15 US disclosed