SCHEMBL5515255

SCHEMBL5515255

CCCCOc1c(C=C2N(C)c3ccccc3C2(C)C)c(=O)c1=O

nearest known ligand 0.48

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 11/20 0.48
HTT P42858 9/20 0.48
MEN1 O00255 8/20 0.48
KMT2A Q03164 8/20 0.48
SMN1; SMN2 Q16637 7/20 0.48
ALDH1A1 P00352 5/20 0.48
GPR55 Q9Y2T6 2/20 0.48
GLA P06280 1/20 0.48
GAA P10253 4/20 0.46
USP2 O75604 3/20 0.46
NPSR1 Q6W5P4 1/20 0.46
LMNA P02545 9/20 0.46
KDM4E B2RXH2 7/20 0.44
MAPK1 P28482 4/20 0.43
TSHR P16473 3/20 0.42
THRB P10828 1/20 0.42
RECQL P46063 1/20 0.42
POLB P06746 3/20 0.41
HSD17B10 Q99714 3/20 0.41
CASP1 P29466 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19815786 1.00 MAPT (0.48) MAPTHTTMEN1KMT2ASMN1; SMN2
SCHEMBL14093787 0.90 MAPT (0.51) MAPTHTTMEN1KMT2ASMN1; SMN2
SCHEMBL19815097 0.89 KMT2A (0.41) MAPTHTTMEN1KMT2ASMN1; SMN2
SCHEMBL21314805 0.89 KMT2A (0.41) MAPTHTTMEN1KMT2ASMN1; SMN2
SCHEMBL7750488 0.88 ALDH1A1 (0.46) MAPTHTTMEN1KMT2ASMN1; SMN2
SCHEMBL7745679 0.88 ALDH1A1 (0.46) MAPTHTTMEN1KMT2ASMN1; SMN2
SCHEMBL13103144 0.85 ALDH1A1 (0.38) MAPTHTTMEN1KMT2ASMN1; SMN2
SCHEMBL16328778 0.83 KMT2A (0.39) MAPTHTTMEN1KMT2ASMN1; SMN2
SCHEMBL5009155 0.83 ALDH1A1 (0.38) MAPTHTTMEN1KMT2ASMN1; SMN2
SCHEMBL7701821 0.83 LMNA (0.52) MAPTHTTMEN1KMT2ASMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9841428-B2 Viscosity-sensitive dyes and method SETA BIOMEDICALS, LLC (US) 2017-12-12 US disclosed
US-9841428-B2 Viscosity-sensitive dyes and method SETA BIOMEDICALS, LLC (US) 2017-12-12 US disclosed
US-9841428-B2 Viscosity-sensitive dyes and method SETA BIOMEDICALS, LLC (US) 2017-12-12 US disclosed
US-20160091495-A1 VISCOSITY-SENSITIVE DYES AND METHOD SETA BIOMEDICALS, LLC 2016-03-31 US disclosed
US-20160091495-A1 VISCOSITY-SENSITIVE DYES AND METHOD SETA BIOMEDICALS, LLC 2016-03-31 US disclosed
US-20160091495-A1 VISCOSITY-SENSITIVE DYES AND METHOD SETA BIOMEDICALS, LLC 2016-03-31 US disclosed
US-7411068-B2 Luminescent compounds SETA BIOMEDICALS, LLC 2008-08-12 US disclosed
US-20070281363-A1 Reporter molecules based on squaric, croconic, and/or rhodizonic acid; photoluminescence Terpetschnig, Ewald (US) 2007-12-06 US disclosed
US-20070281363-A1 Reporter molecules based on squaric, croconic, and/or rhodizonic acid; photoluminescence Terpetschnig, Ewald (US) 2007-12-06 US disclosed
US-7250517-B2 Luminescent compounds Terpetschnig, Ewald A. (US) 2007-07-31 US disclosed
US-7250517-B2 Luminescent compounds Terpetschnig, Ewald A. (US) 2007-07-31 US disclosed
US-7250517-B2 Luminescent compounds Terpetschnig, Ewald A. (US) 2007-07-31 US disclosed
US-20040166515-A1 Luminescent compounds TERPETSCHNIG, EWALD A. 2004-08-26 US disclosed
WO-2003087052-A2 DYES AND FLUORESCENT COMPOUNDS TERPETSCHNIG EWALD A (US) 2003-10-23 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20040166515-A1 Luminescent compounds RORC, NR2E3, RORB MAPT 4542/4885HTT 3369/4885MEN1 3748/4885
US-20070281363-A1 Reporter molecules based on squaric, croconic, and/or rhodizonic acid; photoluminescence SPR, SRRT, SQLE MAPT 3790/4885HTT 2663/4885MEN1 2672/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.