Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.56 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.56 |
| ▸ | TSHR | P16473 | 2/20 | 0.56 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.51 |
| ▸ | GLA | P06280 | 1/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.49 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.49 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.49 |
| ▸ | MEN1 | O00255 | 2/20 | 0.48 |
| ▸ | HPGD | P15428 | 3/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.47 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.47 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.47 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.47 |
| ▸ | RELA | Q04206 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 2/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9234683 | 1.00 | ALDH1A1 (0.56) | ALDH1A1MAPK1TSHRTRPA1KMT2A | |
| SCHEMBL13775156 | 1.00 | ALDH1A1 (0.56) | ALDH1A1MAPK1TSHRTRPA1KMT2A | |
| SCHEMBL23966494 | 0.84 | ALDH1A1 (0.41) | ALDH1A1MAPK1TSHRTRPA1KMT2A | |
| SCHEMBL9674944 | 0.82 | ALDH1A1 (0.38) | ALDH1A1MAPK1TSHRTRPA1KMT2A | |
| SCHEMBL9674953 | 0.82 | ALDH1A1 (0.38) | ALDH1A1MAPK1TSHRTRPA1KMT2A | |
| SCHEMBL23966516 | 0.82 | ALDH1A1 (0.41) | ALDH1A1MAPK1TSHRTRPA1KMT2A | |
| SCHEMBL23914731 | 0.81 | ALDH1A1 (0.55) | ALDH1A1MAPK1TSHRTRPA1KMT2A | |
| SCHEMBL10444039 | 0.81 | HCAR2 (0.51) | ALDH1A1MAPK1TSHRTRPA1KMT2A | |
| SCHEMBL10444040 | 0.81 | HCAR2 (0.51) | ALDH1A1MAPK1TSHRTRPA1KMT2A | |
| SCHEMBL8767801 | 0.81 | NPSR1 (0.48) | ALDH1A1MAPK1TSHRTRPA1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-7173145-A | — | — | None | — | — | JP | disclosed |
| WO-2008093920-A2 | 1,2-DIHYDRO-1-OXOPHTHALAZINYL DERIVATIVES HAVING BIOLOGICAL ACTIVITY ON SEROTONIN RECEPTORS 5-HT2A AND 5-HT2C, AND PREPARATION THEREOF | DONGBU HITEK CO., LTD. (KR) | 2008-08-07 | — | — | WO | disclosed |
| JP-H07173145-A | PRODUCTION OF 3-PHTHALIDYLIDENEACETIC ACID ALKYL ESTER | SUMIKA FINE CHEM KK | 1995-07-11 | — | — | JP | disclosed |
| EP-0295051-B1 | PREPARATION OF OXOPHTHALAZINYL ACETIC ACIDS HAVING BENZOTHIAZOLE OR OTHER HETEROCYCLIC SIDE CHAINS | PFIZER INC. (US) | 1993-06-09 | — | — | EP | disclosed |
| US-4900844-A | Intermediates for the preparation of oxophthalazinyl acetic acids having benzothiazole or other heterocyclic side chains | PFIZER INC. (US) | 1990-02-13 | — | — | US | disclosed |
| US-4868301-A | Processes and intermediates for the preparation of oxophthalazinyl acetic acids having benzothiazole or other heterocyclic side chains | PFIZER INC. (US) | 1989-09-19 | — | — | US | disclosed |
| EP-0295051-A2 | Preparation of oxophthalazinyl acetic acids having benzothiazole or other heterocyclic side chains | PFIZER INC. (US) | 1988-12-14 | — | — | EP | disclosed |