SCHEMBL5009684

SCHEMBL5009684

O=C1OCCOC(=O)c2ccc1cc2O

nearest known ligand 0.43

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALOX5 P09917 1/20 0.43
PRF1 P14222 5/20 0.40
APP P05067 3/20 0.38
MAOA P21397 2/20 0.37
MAOB P27338 2/20 0.37
ADORA3 P0DMS8 1/20 0.36
ADORA2A P29274 1/20 0.36
ADORA1 P30542 1/20 0.36
CNR2 P34972 1/20 0.36
MAPT P10636 3/20 0.35
KDM4E B2RXH2 2/20 0.35
MEN1 O00255 2/20 0.35
ALDH1A1 P00352 2/20 0.35
HPGD P15428 2/20 0.35
KMT2A Q03164 2/20 0.35
SMN1; SMN2 Q16637 2/20 0.35
NPC1 O15118 1/20 0.35
TP53 P04637 1/20 0.35
ALOX15 P16050 1/20 0.35
TSHR P16473 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5520002 0.78 PRF1 (0.38) PRF1MAOAMAOBMAPTKDM4E
SCHEMBL27848386 0.78 PRF1 (0.45) PRF1KDM4EALDH1A1HPGDKMT2A
SCHEMBL3390782 0.77 PRF1 (0.34) ALOX5PRF1MAPTALOX15HSD17B10
SCHEMBL1366417 0.76 PSMB5 (0.41) PRF1MAOAMAOBMAPTKDM4E
SCHEMBL31018377 0.76 PSMB5 (0.41) PRF1MAOAMAOBMAPTKDM4E
SCHEMBL3874923 0.75 ITGB2 (0.43) PRF1MAOAMAOBMAPTKDM4E
SCHEMBL17628649 0.75 ITGB2 (0.43) PRF1MAOAMAOBMAPTKDM4E
SCHEMBL22419 0.75 ITGB2 (0.43) PRF1MAOAMAOBMAPTKDM4E
SCHEMBL4378541 0.74 MAOA (0.38) PRF1MAOAMAOBADORA3MAPT
SCHEMBL7799448 0.74 PRF1 (0.40) PRF1MAPTKDM4EMEN1ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 17 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-104582927-B There is the molded body of specific section structure 株式会社钟化 2016-12-07 CN disclosed
CN-105829383-A POLYURETHANEUREAS OR POLYUREAS 科思创有限公司 2016-08-03 CN disclosed
CN-104582927-A Moulded body having specific cross-sectional structure KANEKA CORP 2015-04-29 CN disclosed
CN-104254569-A Polycarbonate resin composition with superior fluidity and molding thereof KANEKA CORP 2014-12-31 CN disclosed
US-8202591-B2 Polyester resin, molded object thereof, and processes for producing these ASAHI KASEI CHEMICALS CORPORATION (JP) 2012-06-19 US disclosed
US-20080260979-A1 Polyester Resin, Molded Object Thereof, and Processes for Producing these ASAHI KASEI CHEMICALS CORPORATION (JP) 2008-10-23 US disclosed
EP-1818352-A1 POLYESTER RESIN, MOLDED OBJECT THEREOF, AND PROCESSES FOR PRODUCING THESE Asahi Kasei Chemicals Corporation (JP) 2007-08-15 EP disclosed
CN-1247649-C One-step method polyurethane-urea elastomer with light stability BAYER CORP (US) 2006-03-29 CN disclosed
CN-1412214-A One-step method polyurethane-urea elastomer with light stability BAYER AG (US) 2003-04-23 CN disclosed
EP-0707562-B1 PRODUCTION OF DICARBOXYLIC ACIDS DU PONT (US) 2000-04-26 EP disclosed
US-5886057-A COMMINUTING SOLID POLYESTER, REACTING COMMINUTED POLYESTER WITH DIOL IN THE ABSENCE OF WATER AT A POLYESTER:DIOL RATIO OF AT LEAST 1:1 BY WEIGHT, REMOVING DIOL FROM THE LIQUID PHASE MEDIUM, SUBJECTING LIQUID PHASE TO HYDROLYSIS E. I. DU PONT DE NEMOURS AND COMPANY (US) 1999-03-23 US disclosed
EP-0707563-B1 PRODUCTION OF DICARBOXYLIC ACIDS OR ESTERS THEREOF DU PONT (US) 1999-02-17 EP disclosed
US-5750776-A DEPOLYMERIZATION OF SOLID PHASE POLYESTERS IMPERIAL CHEMICAL INDUSTRIES PLC (GB) 1998-05-12 US disclosed
EP-0707562-A1 PRODUCTION OF DICARBOXYLIC ACIDS IMPERIAL CHEMICAL INDUSTRIES PLC (GB) 1996-04-24 EP disclosed
EP-0707563-A1 PRODUCTION OF DICARBOXYLIC ACIDS OR ESTERS THEREOF IMPERIAL CHEMICAL INDUSTRIES PLC (GB) 1996-04-24 EP disclosed
WO-1995001954-A1 PRODUCTION OF DICARBOXYLIC ACIDS OR ESTERS THEREOF IMPERIAL CHEMICAL INDUSTRIES PLC (GB) 1995-01-19 WO disclosed
WO-1995001953-A1 PRODUCTION OF DICARBOXYLIC ACIDS IMPERIAL CHEMICAL INDUSTRIES PLC (GB) 1995-01-19 WO disclosed