SCHEMBL5009896

SCHEMBL5009896

Cn1nc(CCCCO)c(NC=O)c1NC(c1ccccc1)(c1ccccc1)c1ccccc1

nearest known ligand 0.32

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
LTB4R Q15722 1/20 0.32
TERT O14746 1/20 0.31
CNR2 P34972 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5148648 0.67 POLB (0.34) CNR2
SCHEMBL4199889 0.67 GAA (0.32)
SCHEMBL4206940 0.67 CNR2 (0.31) CNR2
SCHEMBL4199230 0.66 BRD9 (0.36)
SCHEMBL4206941 0.64 HTT (0.41) CNR2
Carbamic Acid SCHEMBL3119239 0.64 BRD4 (0.32)
Carbamic Acid SCHEMBL3119184 0.64 BRD4 (0.32)
SCHEMBL5148585 0.63 MEN1 (0.38)
SCHEMBL5148558 0.62 MEN1 (0.33)
SCHEMBL4205063 0.61 ALDH1A1 (0.36)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1994035-A1 CEPHEM COMPOUNDS AND USE AS ANTIMICROBIAL AGENTS Astellas Pharma Inc. (JP) 2008-11-26 EP disclosed
WO-2007119511-A1 CEPHEM COMPOUNDS AND USE AS ANTIMICROBIAL AGENTS ASTELLAS PHARMA INC. (JP) 2007-10-25 WO disclosed