SCHEMBL5010134

SCHEMBL5010134

C[C](Cc1ccccc1-c1ccccc1)c1ccccc1

nearest known ligand 0.48

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
DPP4 P27487 1/20 0.48
PDCD1 Q15116 1/20 0.47
CD274 Q9NZQ7 1/20 0.47
KMT2A Q03164 1/20 0.46
FOLH1 Q04609 2/20 0.40
ALDH1A1 P00352 1/20 0.39
HPGD P15428 1/20 0.39
BCL2L1 Q07817 1/20 0.39
HSD17B10 Q99714 1/20 0.39
PTGDR2 Q9Y5Y4 1/20 0.38
TDP1 Q9NUW8 1/20 0.38
L3MBTL1 Q9Y468 1/20 0.38
HDAC3 O15379 1/20 0.37
HDAC1 Q13547 1/20 0.37
HDAC2 Q92769 1/20 0.37
HDAC6 Q9UBN7 1/20 0.37
SLC6A2 P23975 1/20 0.37
SLC6A4 P31645 1/20 0.37
PTGER1 P34995 2/20 0.37
PTGER4 P35408 2/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28173176 0.82 DPP4 (0.54) DPP4PDCD1CD274KMT2AFOLH1
SCHEMBL5010171 0.81 PTGER4 (0.49) DPP4PDCD1CD274KMT2AFOLH1
SCHEMBL5008804 0.79 PTGER1 (0.43) DPP4PDCD1CD274KMT2AFOLH1
SCHEMBL27457156 0.78 KMT2A (0.56) DPP4PDCD1CD274KMT2AFOLH1
SCHEMBL5527927 0.77 KMT2A (0.55) DPP4KMT2AFOLH1ALDH1A1HPGD
SCHEMBL28214173 0.76 DPP4 (0.47) DPP4PDCD1CD274KMT2AFOLH1
SCHEMBL30887010 0.76 KMT2A (0.53) DPP4PDCD1CD274KMT2AFOLH1
SCHEMBL5048474 0.76 KMT2A (0.53) DPP4PDCD1CD274KMT2AFOLH1
Hydrogen Sulfide SCHEMBL28029149 0.76 KMT2A (0.53) DPP4KMT2AFOLH1ALDH1A1HPGD
SCHEMBL28165717 0.76 DPP4 (0.42) DPP4PDCD1CD274KMT2AFOLH1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20080207864-A1 Organosilanes, Process For Production of the Same, and Use Thereof SHARP KABUSHIKI KAISHA (JP) 2008-08-28 US disclosed