SCHEMBL5010171

SCHEMBL5010171

C[C](CCc1ccccc1-c1ccccc1)c1ccccc1

nearest known ligand 0.49

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PTGER4 P35408 6/20 0.49
PTGER3 P43115 6/20 0.49
PTGER1 P34995 5/20 0.49
PTGER2 P43116 5/20 0.49
DPP4 P27487 1/20 0.46
PDCD1 Q15116 1/20 0.44
CD274 Q9NZQ7 1/20 0.44
KMT2A Q03164 1/20 0.43
FFAR1 O14842 2/20 0.42
FFAR4 Q5NUL3 2/20 0.42
FOLH1 Q04609 3/20 0.41
CA12 O43570 1/20 0.41
CA1 P00915 1/20 0.41
CA2 P00918 1/20 0.41
CA7 P43166 1/20 0.41
CA9 Q16790 1/20 0.41
CA14 Q9ULX7 1/20 0.41
HDAC3 O15379 1/20 0.39
HDAC1 Q13547 1/20 0.39
HDAC2 Q92769 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5008804 0.90 PTGER1 (0.43) PTGER4PTGER3PTGER1PTGER2DPP4
SCHEMBL5010134 0.81 DPP4 (0.48) PTGER4PTGER3PTGER1PTGER2DPP4
SCHEMBL12225988 0.80 PTGER4 (0.58) PTGER4PTGER3PTGER1PTGER2DPP4
SCHEMBL11333152 0.76 DPP4 (0.65) PTGER4PTGER3PTGER1PTGER2DPP4
SCHEMBL1261128 0.76 PTGER4 (0.77) PTGER4PTGER3PTGER1PTGER2DPP4
SCHEMBL31212507 0.76 PTGER4 (0.77) PTGER4PTGER3PTGER1PTGER2DPP4
SCHEMBL27442369 0.76 PTGER4 (0.62) PTGER4PTGER3PTGER1PTGER2DPP4
SCHEMBL6287286 0.75 PTGER4 (0.53) PTGER4PTGER3PTGER1PTGER2DPP4
SCHEMBL429540 0.74 DPP4 (0.58) PTGER4PTGER3PTGER1PTGER2DPP4
SCHEMBL27840283 0.74 DPP4 (0.58) PTGER4PTGER3PTGER1PTGER2DPP4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20080207864-A1 Organosilanes, Process For Production of the Same, and Use Thereof SHARP KABUSHIKI KAISHA (JP) 2008-08-28 US disclosed