Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 4/20 | 0.46 |
| ▸ | GALR2 | O43603 | 1/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 3/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.42 |
| ▸ | PIM3 | Q86V86 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 3/20 | 0.39 |
| ▸ | HTT | P42858 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.38 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | GRIK1 | P39086 | 1/20 | 0.38 |
| ▸ | GRIA1 | P42261 | 1/20 | 0.38 |
| ▸ | GRIA2 | P42262 | 1/20 | 0.38 |
| ▸ | GRIA3 | P42263 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5010795 | 0.78 | LMNA (0.41) | LMNAGALR2POLBTSHRCYP3A4 | |
| SCHEMBL4586058 | 0.75 | IDO1 (0.30) | — | |
| SCHEMBL4867772 | 0.72 | — | — | |
| SCHEMBL28270438 | 0.70 | CYP3A4 (0.50) | LMNAPOLBTSHRCYP3A4MAPT | |
| SCHEMBL31565807 | 0.70 | HSD17B10 (0.54) | TSHRMAPTNPSR1ALDH1A1GPR35 | |
| SCHEMBL11027917 | 0.70 | HSD17B10 (0.54) | TSHRMAPTNPSR1ALDH1A1GPR35 | |
| SCHEMBL17726589 | 0.69 | TDP1 (0.46) | LMNAPOLBTSHRCYP3A4MAPT | |
| SCHEMBL8688932 | 0.69 | TSHR (0.55) | LMNAGALR2POLBTSHRCYP3A4 | |
| SCHEMBL1754836 | 0.68 | P2RY6 (0.39) | LMNAGALR2POLBTSHRCYP3A4 | |
| SCHEMBL11203665 | 0.67 | CASP6 (0.59) | LMNATSHRCYP3A4MAPTALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080207864-A1 | Organosilanes, Process For Production of the Same, and Use Thereof | SHARP KABUSHIKI KAISHA (JP) | 2008-08-28 | — | — | US | disclosed |