SCHEMBL5010349

SCHEMBL5010349

CCC/C=C(\OC)C([O])=O

nearest known ligand 0.34

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 2/20 0.34
TAS1R3 Q7RTX0 1/20 0.33
TAS1R1 Q7RTX1 1/20 0.33
GRIK1 P39086 1/20 0.32
GRIK2 Q13002 1/20 0.32
CA1 P00915 1/20 0.32
CA2 P00918 1/20 0.32
CYP3A4 P08684 2/20 0.32
CYP2C9 P11712 2/20 0.32
CYP2C19 P33261 2/20 0.32
CYP2D6 P10635 1/20 0.32
TSHR P16473 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL454676 0.82 GRIK1 (0.40) ALDH1A1TAS1R3TAS1R1GRIK1GRIK2
SCHEMBL27633832 0.82 TAS1R3 (0.37) ALDH1A1TAS1R3TAS1R1GRIK1GRIK2
SCHEMBL1556036 0.80 GRIK1 (0.35) TAS1R3TAS1R1GRIK1GRIK2CA1
SCHEMBL18570381 0.76
SCHEMBL24021216 0.72 KDM4E (0.32) ALDH1A1CYP3A4CYP2C9CYP2C19CYP2D6
SCHEMBL27595112 0.72 MGAM (0.38) ALDH1A1TAS1R3TAS1R1CA1CA2
SCHEMBL15673159 0.70 EP300 (0.39) ALDH1A1TAS1R3TAS1R1GRIK1GRIK2
SCHEMBL1486764 0.70 GRIK1 (0.41) ALDH1A1TAS1R3TAS1R1GRIK1GRIK2
SCHEMBL1036474 0.70 EP300 (0.48) GRIK1CA1CA2TSHR
SCHEMBL15750768 0.69

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8450033-B2 Electrography; facsimiles, printers, copiers; polyurethanes RICOH COMPANY, LTD. (JP) 2013-05-28 US disclosed
US-20080138728-A1 LATENT ELECTROSTATIC IMAGE BEARING MEMBER, AND IMAGE FORMING APPARATUS, IMAGE FORMING METHOD AND PROCESS CARTRIDGE USING THE SAME RICOH COMPANY, LTD. (JP) 2008-06-12 US disclosed