Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRIK1 | P39086 | 1/20 | 0.35 |
| ▸ | GRIK2 | Q13002 | 1/20 | 0.35 |
| ▸ | FAAH | O00519 | 3/20 | 0.32 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.32 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.32 |
| ▸ | BACE1 | P56817 | 1/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.31 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.31 |
| ▸ | CA1 | P00915 | 1/20 | 0.31 |
| ▸ | CA2 | P00918 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | TP53 | P04637 | 1/20 | 0.31 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.31 |
| ▸ | SOAT1 | P35610 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.31 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.31 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
| ▸ | RAB9A | P51151 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6048387 | 0.88 | GRIK1 (0.39) | GRIK1FAAHCYP3A4CYP2C19CA1 | |
| SCHEMBL1712249 | 0.84 | EP300 (0.48) | FAAHCYP3A4CYP2C19MEN1TP53 | |
| SCHEMBL1712244 | 0.84 | EP300 (0.48) | FAAHCYP3A4CYP2C19MEN1TP53 | |
| SCHEMBL7104263 | 0.82 | — | — | |
| SCHEMBL554691 | 0.82 | — | — | |
| SCHEMBL15015528 | 0.81 | ALOX15 (0.44) | GRIK1GRIK2FAAHBACE1CYP1A2 | |
| SCHEMBL5010349 | 0.80 | ALDH1A1 (0.34) | GRIK1GRIK2TAS1R3TAS1R1CYP3A4 | |
| SCHEMBL27633832 | 0.80 | TAS1R3 (0.37) | GRIK1GRIK2TAS1R3TAS1R1CYP3A4 | |
| SCHEMBL454676 | 0.80 | GRIK1 (0.40) | GRIK1GRIK2TAS1R3TAS1R1CYP3A4 | |
| SCHEMBL27846100 | 0.79 | TSHR (0.33) | GRIK1GRIK2ALOX15RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 31 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3200840-B1 | LOW-WATER CONTENT ACRYLATE-ACRYLAMIDE COPOLYMERS FOR OPHTHALMIC DEVICES | ALCON INC (CH) | 2021-11-17 | — | — | EP | claimed |
| US-20160291019-A1 | System for Detecting Rare Cells | THE REGENTS OF THE UNIVERSITY OF MICHIGAN | 2016-10-06 | — | — | US | claimed |
| US-8673988-B2 | Graft copolymers for ion exchange chromatography | MERCK PATENT GMBH (DE) | 2014-03-18 | — | — | US | claimed |
| JP-2011529508-A | — | — | 2011-12-08 | — | — | JP | claimed |
| US-20110136925-A1 | GRAFT COPOLYMERS FOR ION EXCHANGE CHROMATOGRAPHY | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 2011-06-09 | — | — | US | claimed |
| EP-2310104-A1 | GRAFT COPOLYMERS FOR ION EXCHANGE CHROMATOGRAPHY | Merck Patent GmbH (DE) | 2011-04-20 | — | — | EP | claimed |
| EP-2153877-A1 | Mixed graft polymers for ion exchange chromatography | MERCK PATENT GmbH (DE) | 2010-02-17 | — | — | EP | claimed |
| WO-2010012358-A1 | GRAFT COPOLYMERS FOR ION EXCHANGE CHROMATOGRAPHY | MERCK PATENT GMBH (DE) | 2010-02-04 | — | — | WO | claimed |
| EP-4724118-A1 | TISSUE-PLASMINOGEN ACTIVATOR COATED CATHETER WITH HYDROGEL-CONTROLLED ELUTION | Becton, Dickinson and Company (US) | 2026-04-15 | — | — | EP | disclosed |
| CN-120005093-A | Polymeric excipients for biopharmaceutical formulations | 小利兰斯坦福大学董事会 | 2025-05-16 | — | — | CN | disclosed |
| EP-4529550-A1 | POLYMER EXCIPIENTS COMPRISING N,N-DIETHYLACRYLAMIDE (DEA) FOR BIOPHARMACEUTICAL FORMULATIONS | Surf Bio, Inc. (US) | 2025-04-02 | — | — | EP | disclosed |
| US-20250051502-A1 | POLYMER EXCIPIENTS FOR BIOPHARMACEUTICAL FORMULATIONS | THE BOARD OF TRUSTEES OF THE LELAND STANFORD JUNIOR UNIVERSITY | 2025-02-13 | — | — | US | disclosed |
| US-12187828-B2 | Polymer excipients for biopharmaceutical formulations | THE BOARD OF TRUSTEES OF THE LELAND STANFORD JUNIOR UNIVERISTY (US) | 2025-01-07 | — | — | US | disclosed |
| CN-115698106-B | Polymeric excipients for biopharmaceutical formulations | 小利兰斯坦福大学董事会 | 2025-01-07 | — | — | CN | disclosed |
| EP-2310104-B1 | MIXED GRAFT POLYMERS FOR ION EXCHANGE CHROMATOGRAPHY | MERCK PATENT GMBH (DE) | 2017-10-18 | — | — | EP | disclosed |
| US-8673988-B2 | Graft copolymers for ion exchange chromatography | MERCK PATENT GMBH (DE) | 2014-03-18 | — | — | US | disclosed |
| US-20110136925-A1 | GRAFT COPOLYMERS FOR ION EXCHANGE CHROMATOGRAPHY | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 2011-06-09 | — | — | US | disclosed |
| EP-2310104-A1 | GRAFT COPOLYMERS FOR ION EXCHANGE CHROMATOGRAPHY | Merck Patent GmbH (DE) | 2011-04-20 | — | — | EP | disclosed |
| EP-2153877-A1 | Mixed graft polymers for ion exchange chromatography | MERCK PATENT GmbH (DE) | 2010-02-17 | — | — | EP | disclosed |
| WO-2010012358-A1 | GRAFT COPOLYMERS FOR ION EXCHANGE CHROMATOGRAPHY | MERCK PATENT GMBH (DE) | 2010-02-04 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-12187828-B2 | Polymer excipients for biopharmaceutical formulations | IAPP, PNLIP, INSRR | GRIK1 4222/4885GRIK2 4415/4885FAAH 2225/4885 |
| US-20250051502-A1 | POLYMER EXCIPIENTS FOR BIOPHARMACEUTICAL FORMULATIONS | IAPP, PNLIP, INSRR | GRIK1 4222/4885GRIK2 4415/4885FAAH 2225/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.