Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DGKA | P23743 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | DNM1 | Q05193 | 1/20 | 0.33 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.32 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.32 |
| ▸ | HTR2C | P28335 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 2/20 | 0.32 |
| ▸ | BLM | P54132 | 1/20 | 0.32 |
| ▸ | NAAA | Q02083 | 1/20 | 0.31 |
| ▸ | THRB | P10828 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
| ▸ | POLB | P06746 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8752134 | 0.89 | DGKA (0.54) | DGKAALDH1A1KMT2AMEN1DNM1 | |
| SCHEMBL28846310 | 0.89 | DGKA (0.49) | DGKAALDH1A1KMT2AMEN1DNM1 | |
| SCHEMBL8752085 | 0.88 | DGKA (0.57) | DGKAALDH1A1KMT2AMEN1DNM1 | |
| SCHEMBL22331133 | 0.88 | DGKA (0.57) | DGKAALDH1A1KMT2AMEN1DNM1 | |
| SCHEMBL8752108 | 0.88 | DGKA (0.57) | DGKAALDH1A1KMT2AMEN1DNM1 | |
| SCHEMBL8752032 | 0.88 | DGKA (0.57) | DGKAALDH1A1KMT2AMEN1DNM1 | |
| SCHEMBL8752071 | 0.88 | DGKA (0.57) | DGKAALDH1A1KMT2AMEN1DNM1 | |
| SCHEMBL8752067 | 0.88 | DGKA (0.57) | DGKAALDH1A1KMT2AMEN1DNM1 | |
| SCHEMBL4613311 | 0.88 | MEN1 (0.39) | DGKAKMT2AMEN1ADRA2AADRA1A | |
| SCHEMBL13044432 | 0.87 | DGKA (0.38) | DGKAALDH1A1KMT2AMEN1DNM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080194887-A1 | SEPARATION OF FLUOROUS COMPOUNDS | PITTSBURGH UNIVERSITY OF - OF THE COMMONWEALTH SYSTEM OF HIGHER EDUCATION | 2008-08-14 | — | — | US | disclosed |
| US-7364908-B2 | Separation of fluorous compounds | UNIVERSITY OF PITTSBURGH - OF THE COMMONWEALTH SYSTEM OF HIGHER EDUCATION (US) | 2008-04-29 | — | — | US | disclosed |
| US-20050283032-A1 | charging a mixture of compounds to a non-fluorous solid phase (silica gel, alumina, zirconia) and eluting with a fluorous eluting fluid (hydrofluoroalkane, a hydrofluoroether, a hydrofluoroamine, a perfluoroalkane, a perfluoroether, or a perfluoroamine) and a cosolvent: difference in fluorous nature | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2005-12-22 | — | — | US | disclosed |