SCHEMBL8752134

SCHEMBL8752134

CCCCCC(=O)OCCC(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)F

nearest known ligand 0.54

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
DGKA P23743 1/20 0.54
DNM1 Q05193 1/20 0.46
PAM P19021 2/20 0.42
PRSS1 P07477 1/20 0.41
PRSS2 P07478 1/20 0.41
PRSS3 P35030 1/20 0.41
TSHR P16473 1/20 0.41
MAPT P10636 1/20 0.41
FAAH O00519 4/20 0.40
LMNA P02545 2/20 0.40
ALDH1A1 P00352 1/20 0.40
KDM4E B2RXH2 1/20 0.39
DUSP3 P51452 1/20 0.39
MEN1 O00255 1/20 0.39
KMT2A Q03164 1/20 0.39
HTR2C P28335 1/20 0.39
CES1 P23141 2/20 0.39
NAAA Q02083 1/20 0.39
CES2 O00748 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8752108 0.98 DGKA (0.57) DGKADNM1PAMPRSS1PRSS2
SCHEMBL8752067 0.98 DGKA (0.57) DGKADNM1PAMPRSS1PRSS2
SCHEMBL8752032 0.98 DGKA (0.57) DGKADNM1PAMPRSS1PRSS2
SCHEMBL8752085 0.98 DGKA (0.57) DGKADNM1PAMPRSS1PRSS2
SCHEMBL22331133 0.98 DGKA (0.57) DGKADNM1PAMPRSS1PRSS2
SCHEMBL8752071 0.98 DGKA (0.57) DGKADNM1PAMPRSS1PRSS2
SCHEMBL22331132 0.97 DGKA (0.59) DGKADNM1PAMPRSS1PRSS2
SCHEMBL28846310 0.94 DGKA (0.49) DGKADNM1PAMPRSS1PRSS2
SCHEMBL29098826 0.92 DGKA (0.40) DGKADNM1PAMPRSS1PRSS2
SCHEMBL9223606 0.91 MGLL (0.50) DGKAMAPTFAAHALDH1A1CES1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0737508-B1 Use of hydrofluorocarbon compound in an emulsion, emulsion and composition containing the same OREAL (FR) 1997-04-16 EP claimed
EP-0737508-A1 Use of hydrofluorocarbon compound in an emulsion, emulsion and composition containing the same L'OREAL (FR) 1996-10-16 EP disclosed