SCHEMBL5010776

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL5013503	0.89	PPARG (0.50)	GAAALDH1A1SMN1; SMN2CYP1A2CYP2C19
	SCHEMBL5009734	0.89	CYP1A2 (0.47)	GAAALDH1A1SMN1; SMN2CNR1HPGD
	SCHEMBL14587853	0.89	GAA (0.70)	GAAALDH1A1SMN1; SMN2LMNAHTT
	SCHEMBL5010394	0.88	PPARG (0.51)	GAAALDH1A1SMN1; SMN2CNR1HPGD
	SCHEMBL5010363	0.87	GAA (0.52)	GAASMN1; SMN2LMNAHTTHPGD
	SCHEMBL5012232	0.87	JAK2 (0.48)	GAAALDH1A1SMN1; SMN2LMNACNR1
	SCHEMBL5010405	0.86	PPARG (0.59)	ALDH1A1NPC1RAB9APPARGMMP13
	SCHEMBL5012123	0.84	HPGD (0.50)	ALDH1A1LMNAHPGDNPC1RAB9A
	SCHEMBL5013486	0.83	PPARG (0.54)	GAAALDH1A1SMN1; SMN2LMNAHPGD
	SCHEMBL5012093	0.83	ADORA2A (0.47)	ALDH1A1SMN1; SMN2HTTHPGDCYP1A2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.