Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.40 |
| ▸ | ACHE | P22303 | 1/20 | 0.39 |
| ▸ | SLC6A4 | P31645 | 8/20 | 0.39 |
| ▸ | SLC6A3 | Q01959 | 8/20 | 0.39 |
| ▸ | SLC6A2 | P23975 | 6/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 5/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.39 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.39 |
| ▸ | PLAU | P00749 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5010789 | 1.00 | HCAR2 (0.40) | HCAR2ACHESLC6A4SLC6A3SLC6A2 | |
| SCHEMBL14181458 | 1.00 | HCAR2 (0.40) | HCAR2ACHESLC6A4SLC6A3SLC6A2 | |
| SCHEMBL5011562 | 0.85 | HDAC4 (0.41) | SLC6A4SLC6A3CYP3A4 | |
| SCHEMBL14173018 | 0.85 | HDAC4 (0.41) | SLC6A4SLC6A3CYP3A4 | |
| SCHEMBL5011558 | 0.85 | HDAC4 (0.41) | SLC6A4SLC6A3CYP3A4 | |
| SCHEMBL14173019 | 0.76 | EPHX1 (0.46) | — | |
| SCHEMBL5010892 | 0.76 | EPHX1 (0.46) | — | |
| SCHEMBL5010893 | 0.76 | EPHX1 (0.46) | — | |
| SCHEMBL14173021 | 0.75 | SMN1; SMN2 (0.41) | SLC6A4SLC6A3CYP2D6 | |
| SCHEMBL5014316 | 0.75 | SMN1; SMN2 (0.41) | SLC6A4SLC6A3CYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7388101-B1 | Tetrahydrofuran derivatives having cis substituent, their intermediates, and their preparation method | KOREA INSTITUTE OF SCIENCE AND TECHNOLOGY (KR) | 2008-06-17 | — | — | US | disclosed |