Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX1 | P07099 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.44 |
| ▸ | MAPT | P10636 | 5/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | CES2 | O00748 | 1/20 | 0.40 |
| ▸ | CES1 | P23141 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.39 |
| ▸ | MEN1 | O00255 | 4/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | HTR1E | P28566 | 1/20 | 0.38 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14173019 | 1.00 | EPHX1 (0.46) | EPHX1ALDH1A1MAPTSMN1; SMN2HPGD | |
| SCHEMBL5010892 | 1.00 | EPHX1 (0.46) | EPHX1ALDH1A1MAPTSMN1; SMN2HPGD | |
| SCHEMBL10002218 | 0.91 | EPHX1 (0.45) | EPHX1ALDH1A1MAPTSMN1; SMN2HPGD | |
| SCHEMBL598758 | 0.91 | EPHX1 (0.45) | EPHX1ALDH1A1MAPTSMN1; SMN2HPGD | |
| SCHEMBL5011558 | 0.86 | HDAC4 (0.41) | EPHX1ALDH1A1SMN1; SMN2MAPK1POLB | |
| SCHEMBL14173018 | 0.86 | HDAC4 (0.41) | EPHX1ALDH1A1SMN1; SMN2MAPK1POLB | |
| SCHEMBL5011562 | 0.86 | HDAC4 (0.41) | EPHX1ALDH1A1SMN1; SMN2MAPK1POLB | |
| SCHEMBL5011512 | 0.86 | CES2 (0.46) | EPHX1ALDH1A1MAPTSMN1; SMN2HPGD | |
| SCHEMBL5011510 | 0.86 | CES2 (0.46) | EPHX1ALDH1A1MAPTSMN1; SMN2HPGD | |
| SCHEMBL14173017 | 0.86 | CES2 (0.46) | EPHX1ALDH1A1MAPTSMN1; SMN2HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7388101-B1 | Tetrahydrofuran derivatives having cis substituent, their intermediates, and their preparation method | KOREA INSTITUTE OF SCIENCE AND TECHNOLOGY (KR) | 2008-06-17 | — | — | US | disclosed |