Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TLR8 | Q9NR97 | 7/20 | 0.37 |
| ▸ | PTGS2 | P35354 | 3/20 | 0.36 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.36 |
| ▸ | PPARA | Q07869 | 1/20 | 0.35 |
| ▸ | ELANE | P08246 | 2/20 | 0.35 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.34 |
| ▸ | NR1H3 | Q13133 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.33 |
| ▸ | USP2 | O75604 | 2/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | GAA | P10253 | 2/20 | 0.33 |
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
| ▸ | LIPG | Q9Y5X9 | 1/20 | 0.33 |
| ▸ | GLA | P06280 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | CASP1 | P29466 | 1/20 | 0.33 |
| ▸ | CASP7 | P55210 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5012389 | 0.81 | TLR8 (0.38) | TLR8PTGS2ALOX5PPARANR1H2 | |
| SCHEMBL5010999 | 0.81 | TLR8 (0.41) | TLR8PPARANR1H2NR1H3ALDH1A1 | |
| SCHEMBL5010798 | 0.73 | TLR8 (0.36) | TLR8PTGS2ALOX5PPARAELANE | |
| SCHEMBL19356596 | 0.70 | LIPG (0.50) | TLR8PTGS2ALOX5PPARANR1H2 | |
| SCHEMBL3725216 | 0.68 | KDM4E (0.40) | TLR8PTGS2ALOX5ELANENR1H2 | |
| Pyrene SCHEMBL28277958 | 0.67 | LIPG (0.49) | TLR8MAPTLIPGMEN1KMT2A | |
| SCHEMBL284530 | 0.66 | LIPG (0.55) | TLR8MAPTLIPG | |
| SCHEMBL284785 | 0.66 | LIPG (0.55) | TLR8MAPTLIPG | |
| SCHEMBL284581 | 0.66 | LIPG (0.55) | TLR8MAPTLIPG | |
| SCHEMBL1798754 | 0.66 | LIPG (0.55) | TLR8MAPTLIPG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080207864-A1 | Organosilanes, Process For Production of the Same, and Use Thereof | SHARP KABUSHIKI KAISHA (JP) | 2008-08-28 | — | — | US | disclosed |