SCHEMBL5010798

SCHEMBL5010798

CCCCCCCCCCCCCCCCCCc1cccc2c3c(ccc12)-c1cc([Si](OC)(OC)OC)cc2cccc-3c12

nearest known ligand 0.36

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
TLR8 Q9NR97 9/20 0.36
ELANE P08246 3/20 0.34
CNR1 P21554 2/20 0.33
MAPT P10636 1/20 0.32
ALOX5 P09917 1/20 0.32
PTGS2 P35354 1/20 0.32
MTNR1A P48039 1/20 0.32
CTSG P08311 1/20 0.32
PPARA Q07869 1/20 0.32
KCNH2 Q12809 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5011000 0.82 CNR1 (0.41) TLR8ELANECNR1MAPTCTSG
SCHEMBL5012391 0.82 CYP1B1 (0.40) TLR8ELANECNR1MAPTCTSG
SCHEMBL5010794 0.73 TLR8 (0.37) TLR8ELANEMAPTALOX5PTGS2
SCHEMBL5010999 0.69 TLR8 (0.41) TLR8CNR1MAPTPPARA
SCHEMBL9764124 0.65 LIPG (0.49) TLR8CNR1MAPTKCNH2
SCHEMBL28452662 0.65 LIPG (0.49) TLR8CNR1MAPTKCNH2
SCHEMBL16666257 0.65 LIPG (0.49) TLR8CNR1MAPTKCNH2
SCHEMBL2577637 0.65 LIPG (0.49) TLR8CNR1MAPTKCNH2
SCHEMBL28339808 0.65 LIPG (0.49) TLR8CNR1MAPTKCNH2
SCHEMBL9621111 0.65 LIPG (0.49) TLR8CNR1MAPTKCNH2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20080207864-A1 Organosilanes, Process For Production of the Same, and Use Thereof SHARP KABUSHIKI KAISHA (JP) 2008-08-28 US disclosed