SCHEMBL5010875

SCHEMBL5010875

Cc1ccc(-n2c(-c3ccccc3)ccc2-c2ccccc2)cc1

nearest known ligand 0.59

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPK1 P28482 2/20 0.59
HTT P42858 3/20 0.56
CYP2C9 P11712 1/20 0.56
ALDH1A1 P00352 5/20 0.54
MAPT P10636 4/20 0.54
PKM P14618 2/20 0.54
KDM4E B2RXH2 5/20 0.50
SMN1; SMN2 Q16637 2/20 0.50
HPGD P15428 2/20 0.50
PPARG P37231 1/20 0.50
NCOA2 Q15596 1/20 0.50
NCOA1 Q15788 1/20 0.50
NPC1 O15118 1/20 0.50
RAB9A P51151 1/20 0.50
GAA P10253 1/20 0.50
MEN1 O00255 3/20 0.49
KMT2A Q03164 3/20 0.49
NPSR1 Q6W5P4 1/20 0.49
PTGS2 P35354 2/20 0.49
MYC P01106 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12103473 0.92 MAPK1 (0.53) MAPK1HTTCYP2C9ALDH1A1MAPT
SCHEMBL13231751 0.89 PTGS2 (0.58) MAPK1HTTCYP2C9ALDH1A1MAPT
SCHEMBL12103559 0.86 AVPR1A (0.58) MAPK1HTTCYP2C9ALDH1A1MAPT
SCHEMBL5012633 0.84 ALDH1A1 (0.45) MAPK1HTTCYP2C9ALDH1A1MAPT
SCHEMBL5012632 0.84 ALDH1A1 (0.45) MAPK1HTTCYP2C9ALDH1A1MAPT
SCHEMBL11310071 0.84 MAPT (0.52) MAPK1HTTALDH1A1MAPTPKM
SCHEMBL12103490 0.83 HTT (0.47) MAPK1HTTCYP2C9ALDH1A1MAPT
SCHEMBL15694845 0.82 HTT (0.59) MAPK1HTTCYP2C9ALDH1A1MAPT
SCHEMBL12799580 0.82 PTGS2 (0.66) MAPK1HTTCYP2C9ALDH1A1MAPT
SCHEMBL12770263 0.80 HTT (0.43) MAPK1HTTCYP2C9ALDH1A1MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1389626-B1 Aromatic copolymers of pyrroles and an electroluminescent element using the same KOREA INST SCI & TECH (KR) 2008-12-31 EP disclosed
EP-1389626-B1 Aromatic copolymers of pyrroles and an electroluminescent element using the same KOREA INST SCI & TECH (KR) 2008-12-31 EP disclosed
US-6780950-B2 Pyrrole compounds, polymers thereof and EL element using the same KOREA INSTITUTE OF SCIENCE AND TECHNOLOGY (KR) 2004-08-24 US disclosed
US-20040034189-A1 Pyrrole compounds, polymers thereof and EL element using the same KOREA INSTITUTE OF SCIENCE AND TECHNOLOGY 2004-02-19 US disclosed
EP-1389626-A1 Aromatic copolymers of pyrroles and an electroluminescent element using the same Korea Institute of Science and Technology (KR) 2004-02-18 EP disclosed