Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.34 |
| ▸ | HTT | P42858 | 2/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | PIK3CA | P42336 | 5/20 | 0.34 |
| ▸ | PIK3R1 | P27986 | 4/20 | 0.34 |
| ▸ | MTOR | P42345 | 2/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 5/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.32 |
| ▸ | HPGD | P15428 | 3/20 | 0.32 |
| ▸ | LRRK2 | Q5S007 | 2/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 1/20 | 0.31 |
| ▸ | BLM | P54132 | 2/20 | 0.31 |
| ▸ | GAK | O14976 | 1/20 | 0.31 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.31 |
| ▸ | PIK3CB | P42338 | 1/20 | 0.31 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5012837 | 0.92 | ALDH1A1 (0.38) | KDM4EHTTHSD17B10SMN1; SMN2GAA | |
| SCHEMBL5014312 | 0.87 | HRH3 (0.37) | KDM4EHTTNPC1MTORSMN1; SMN2 | |
| SCHEMBL5012148 | 0.86 | KDM4E (0.33) | KDM4EHTTALDH1A1RAB9A | |
| SCHEMBL5011042 | 0.85 | KDM4E (0.34) | KDM4EHTTGAAALDH1A1RAB9A | |
| SCHEMBL5011046 | 0.85 | KDM4E (0.34) | KDM4EHTTGAAALDH1A1RAB9A | |
| SCHEMBL5012158 | 0.85 | KDM4E (0.34) | KDM4EHTTGAAALDH1A1RAB9A | |
| SCHEMBL5015616 | 0.84 | ALDH1A1 (0.39) | KDM4EHTTNPC1MTORHSD17B10 | |
| SCHEMBL5063593 | 0.83 | KDM4E (0.33) | KDM4EHTTALDH1A1RAB9A | |
| SCHEMBL5012206 | 0.83 | KDM4E (0.33) | KDM4EHTTALDH1A1RAB9A | |
| SCHEMBL5012744 | 0.83 | KDM4E (0.33) | KDM4EHTTALDH1A1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1888597-A2 | ANTIBACTERIAL AGENTS | Warner-Lambert Company LLC (US) | 2008-02-20 | — | — | EP | disclosed |
| WO-2006120563-A2 | ANTIBACTERIAL AGENTS | WARNER-LAMBERT COMPANY LLC (US) | 2006-11-16 | — | — | WO | disclosed |